from Section 1 - The Developmental Context and Developmental Disorders
Published online by Cambridge University Press: 10 March 2021
Schizophrenia is a severe psychiatric disorder that can have a devastating impact on the lives of those affected, their families, and their communities. Schizophrenia can affect both females and males but males tend to have both an earlier onset of symptoms and a worse longitudinal course of illness. This chapter explores the differences between males and females with schizophrenia, with a focus on how this difference impacts upon the lives of men. Areas discussed include prevalence and incidence rates, age at onset, and premorbid function. The role of sex hormones is discussed, followed by an examination of brain pathology and cognition. Symptom profile, response to antipsychotic medication, and psychosocial function post-diagnosis are also addressed. Finally, a typological model is proposed, with the thesis that males are differentially prone to an early-onset severe form of schizophrenia.
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