The catastrophic breakdown in relations with family and friends alike after the débâcle with Lou von Salomé and Paul Rée left Nietzsche isolated from almost everyone in his life. After his mother accused him of having besmirched the name of his father, Nietzsche packed his bags and left Naumburg for Leipzig in September 1882 (cf. KSB 6, 256 and 326); his sister, Elisabeth, was seemingly unable to understand why Nietzsche was so upset by this remark, but we should remember Nietzsche's identification with his father, following his early death. Although the Pindaric imperative, “become who you are” that Nietzsche had earlier drawn to Lou von Salomé's attention (KSB 6, 203) was one that he continued to urge upon her in the form of her “emancipation from her emancipation” (schließlich muß man sich noch von dieser Emancipation emancipiren; KSB 6, 247–48), his discovery that Lou was, as he told Malwida von Meysenbug, “almost a caricature of what I admire as an ideal” (beinahe die Caricatur dessen, was ich als Ideal verehre; KSB 6, 315), had led to complete disillusionment; Nietzsche's attitude became increasingly grim and bleak. Consumed by his emotions “in the school of the affects” (in der Schule der Affekte), and plagued by bad headaches and migraines, he turned to opium for relief (KSB 6, 306–7).