Skip to main content Accessibility help
×
Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-07T20:19:38.015Z Has data issue: false hasContentIssue false

6 - Hot and cold cognition in major depressive disorder

from Part I - Clinical relevance of cognitive dysfunction in major depressive disorder

Published online by Cambridge University Press:  05 March 2016

Roger S. McIntyre
Affiliation:
University of Toronto
Danielle S. Cha
Affiliation:
University of Toronto
Get access
Type
Chapter
Information
Cognitive Impairment in Major Depressive Disorder
Clinical Relevance, Biological Substrates, and Treatment Opportunities
, pp. 69 - 80
Publisher: Cambridge University Press
Print publication year: 2016

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abas, M. A., Sahakian, B. J., & Levy, R. (1990). Neuropsychological deficits and CT scan changes in elderly depressives. Psychological Medicine, 20(3): 507520.Google Scholar
Aleman, A., Hijman, R., de Haan, E. H., & Kahn, R. S. (1999). Memory impairment in schizophrenia: A meta-analysis. American Journal of Psychiatry, 156(9): 13581366.CrossRefGoogle ScholarPubMed
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual Review of Neuroscience, 9: 357381.Google Scholar
Alloway, T. P. & Alloway, R. G. (2010). Investigating the predictive roles of working memory and IQ in academic attainment. Journal of Experimental Child Psychology, 106(1): 2029.Google Scholar
American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders (5th edn.). Arlington, VA: American Psychiatric Publishing.Google Scholar
Bang-Andersen, B., Ruhland, T., Jørgensen, M., Smith, G., Frederiksen, K., Jensen, K. G., … Stensbøl, T. B. (2011). Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): A novel multimodal compound for the treatment of major depressive disorder. Journal of Medicinal Chemistry, 54(9): 32063221.CrossRefGoogle ScholarPubMed
Beats, B. C., Sahakian, B. J., & Levy, R. (1996). Cognitive performance in tests sensitive to frontal lobe dysfunction in the elderly depressed. Psychological Medicine, 26(3): 591603.CrossRefGoogle ScholarPubMed
Beck, A. (1967). Depression: Clinical, Experimental, and Theoretical Aspects. New York: Harper & Row.Google Scholar
Clark, L., Chamberlain, S. R., & Sahakian, B. J. (2009). Neurocognitive mechanisms in depression: Implications for treatment. Annual Review of Neuroscience, 32: 5774.CrossRefGoogle ScholarPubMed
Clark, L., Sarna, A., & Goodwin, G. M. (2005). Impairment of executive function but not memory in first-degree relatives of patients with bipolar I disorder and in euthymic patients with unipolar depression. American Journal of Psychiatry, 162: 19801982.CrossRefGoogle Scholar
Cuthbert, B. & Insel, T. (2013). Toward the future of psychiatric diagnosis: The seven pillars of RDoC. BMC Medicine, 11: 126.CrossRefGoogle ScholarPubMed
di Simplicio, M., Norbury, R., & Harmer, C. J. (2012). Short-term antidepressant administration reduces negative self-referential processing in the medial prefrontal cortex in subjects at risk for depression. Molecular Psychiatry, 17(5): 503510.Google Scholar
Drevets, W. C., Price, J. L., Simpson, J. R., Todd, R. D., Reich, T., Vannier, M., & Raichle, M. E. (1997). Subgenual prefrontal cortex abnormalities in mood disorders. Nature, 386(6627): 824827.CrossRefGoogle ScholarPubMed
Duman, R. S. & Aghajanian, G. K. (2014). Neurobiology of rapid acting antidepressants: Role of BDNF and GSK-3 [beta]. Neuropsychopharmacology, 39(1): 233.Google Scholar
Elliott, R., Rubinsztein, J. S., Sahakian, B. J., & Dolan, R. J. (2000). Selective attention to emotional stimuli in a verbal go/no-go task: An fMRI study. Neuroreport, 11(8): 17391744.Google Scholar
Elliott, R., Sahakian, B. J., Herrod, J. J., Robbins, T. W., & Paykel, E. S. (1997). Abnormal response to negative feedback in unipolar depression: Evidence for a diagnosis specific impairment. Journal of Neurology, Neurosurgery, and Psychiatry, 63(1): 7482.Google Scholar
Elliott, R., Sahakian, B. J., Mckay, A. P., Herrod, J. J., Robbins, T. W., & Paykel, E. S. (1996). Neuropsychological impairments in unipolar depression: The influence of perceived failure on subsequent performance. Psychological Medicine, 26(5): 975989.Google Scholar
Erickson, K., Drevets, W. C., Clark, L., Cannon, D. M., Bain, E. E., Zarate, C. A., … Sahakian, B. J. (2005). Mood-congruent bias in affective Go/No-Go performance of unmedicated patients with major depressive disorder. American Journal of Psychiatry, 162(11): 21712173.CrossRefGoogle ScholarPubMed
Eshel, N. & Roiser, J. P. (2010). Reward and punishment processing in depression. Biological Psychiatry, 68(2): 118124.Google Scholar
Fineberg, N. A., Haddad, P. M., Carpenter, L., Gannon, B., Sharpe, R., Young, A. H., … Sahakian, B. J. (2013). The size, burden and cost of disorders of the brain in the UK. Journal of Psychopharmacology, 27(9): 761770.CrossRefGoogle ScholarPubMed
Friedman, N. P., Miyake, A., Corley, R. P., Young, S. E., Defries, J. C., & Hewitt, J. K. (2006). Not all executive functions are related to intelligence. Psychological Science, 17(2): 172179.Google Scholar
Friston, K. (2005). A theory of cortical responses. Philosophical Transactions of the Royal Society B: Biological Sciences, 360(1456): 815836.Google Scholar
Ghio, L., Gotelli, S., Marcenaro, M., Amore, M., & Natta, W. (2014). Duration of untreated illness and outcomes in unipolar depression: A systematic review and meta-analysis. Journal of Affective Disorders, 152–154: 4551.CrossRefGoogle ScholarPubMed
Goss, A. J., Kaser, M., Costafreda, S. G., Sahakian, B. J., & Fu, C. (2013). Modafinil augmentation therapy in unipolar and bipolar depression: A systematic review and meta-analysis of randomized controlled trials. Journal of Clinical Psychiatry, 74(11): 11011107.Google Scholar
Graham, J., Salimi-Khorshidi, G., Hagan, C., Walsh, N., Goodyer, I., Lennox, B., & Suckling, J. (2013). Meta-analytic evidence for neuroimaging models of depression: State or trait? Journal of Affective Disorders, 151(2): 423431.Google Scholar
Hardy, S. E. (2009). Methylphenidate for the treatment of depressive symptoms, including fatigue and apathy, in medically ill older adults and terminally ill adults. American Journal of Geriatric Pharmacotherapy, 7(1): 3459.Google Scholar
Harmer, C. J. (2008). Serotonin and emotional processing: Does it help explain antidepressant drug action? Neuropharmacology, 55(6): 10231028.Google Scholar
Harmer, C. J., Cowen, P. J., & Goodwin, G. M. (2011). Efficacy markers in depression. Journal of Psychopharmacology, 25: 11481158.Google Scholar
Harmer, C. J., Goodwin, G. M., & Cowen, P. J. (2009a). Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action. British Journal of Psychiatry, 195(2): 102108.CrossRefGoogle Scholar
Harmer, C. J., O’Sullivan, U., Favaron, E., Massey-Chase, R., Ayres, R., Reinecke, A., … Cowen, P. (2009b). Effect of acute antidepressant administration on negative affective bias in depressed patients. American Journal of Psychiatry, 166: 11781184.Google Scholar
Harvey, P.-O., Fossati, P., Pochon, J.-B., Levy, R., Lebastard, G., Lehéricy, S., … Dubois, B. (2005). Cognitive control and brain resources in major depression: An fMRI study using the n-back task. NeuroImage, 26(3): 860869.Google Scholar
Insel, T. R. & Gogtay, N. (2014). National Institute of Mental Health clinical trials: New opportunities, new expectations. JAMA Psychiatry, 71(7): 745746.Google Scholar
Insel, T. R., Sahakian, B. J., Voon, V., Nye, J., Brown, V. J., Altevogt, B. M., … Williams, J. H. (2012). Drug research: A plan for mental illness. Nature, 483(7389): 269.Google Scholar
Insel, T. R., Voon, V., Nye, J. S., Brown, V. J., Altevogt, B. M., Bullmore, E. T., … Sahakian, B. J. (2013). Innovative solutions to novel drug development in mental health. Neuroscience & Biobehavioral Reviews, 37(10): 24382444.Google Scholar
Jaeger, J., Berns, S., Uzelac, S., & Davis-Conway, S. (2006). Neurocognitive deficits and disability in major depressive disorder. Psychiatry Research, 145(1): 3948.Google Scholar
Katona, C., Hansen, T., & Olsen, C. K. (2012). A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder. International Clinical Psychopharmacology, 27(4): 215223.Google Scholar
Kennedy, S. H., Evans, K. R., Krüger, S., Mayberg, H. S., Meyer, J. H., McCann, S., … Vaccarino, F. J. (2001). Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression. American Journal of Psychiatry, 158(6): 899905.CrossRefGoogle ScholarPubMed
Kennedy, S. H., Giacobbe, P., Rizvi, S. J., Placenza, F. M., Nishikawa, Y., Mayberg, H. S., & Lozano, A. M. (2011). Deep brain stimulation for treatment-resistant depression: Follow-up after 3 to 6 years. American Journal of Psychiatry, 168(5): 502510.Google Scholar
Kyte, Z. A., Goodyer, I. M., & Sahakian, B. J. (2005). Selected executive skills in adolescents with recent first episode major depression. Journal of Child Psychology and Psychiatry, 46(9): 9951005.Google Scholar
Luckenbaugh, D. A., Niciu, M. J., Ionescu, D. F., Nolan, N. M., Richards, E. M., Brutsche, N. E., … Zarate, C. A. (2014). Do the dissociative side effects of ketamine mediate its antidepressant effects? Journal of Affective Disorders, 159: 5661.Google Scholar
Maalouf, F. T., Clark, L., Tavitian, L., Sahakian, B. J., Brent, D., & Phillips, M. L. (2012). Bias to negative emotions: A depression state-dependent marker in adolescent major depressive disorder. Psychiatry Research, 198(1): 2833.Google Scholar
Malhotra, A. K., Pinals, D. A., Weingartner, H., Sirocco, K., Missar, C. D., Pickar, D., & Breier, A. (1996). NMDA receptor function and human cognition: The effects of ketamine in healthy volunteers. Neuropsychopharmacology, 14(5): 301307.CrossRefGoogle ScholarPubMed
Martinussen, R., Hayden, J., Hogg-Johnson, S., & Tannock, R. (2005). A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 44(4): 377384.Google Scholar
McIntyre, R. S., Lophaven, S., & Olsen, C. K. (2014). A randomized, double-blind, placebo-controlled study of vortioxetine on cognitive function in depressed adults. International Journal of Neuropsychopharmacology, 17(10): 15571567.Google Scholar
Mehta, M. A., Owen, A. M., Sahakian, B. J., Mavaddat, N., Pickard, J. D., & Robbins, T. W. (2000). Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain. Journal of Neuroscience, 20(6): RC65.Google Scholar
Mørk, A., Pehrson, A., Brennum, L. T., Nielsen, S. M., Zhong, H., Lassen, A. B., … Stensbøl, T. B. (2012). Pharmacological effects of Lu AA21004: A novel multimodal compound for the treatment of major depressive disorder. Journal of Pharmacology and Experimental Therapeutics, 340(3): 666675.Google Scholar
Müller, U., Rowe, J. B., Rittman, T., Lewis, C., Robbins, T. W., & Sahakian, B. J. (2013). Effects of modafinil on oligem cognition, task enjoyment and creative thinking in healthy volunteers. Neuropharmacology, 64: 490495.Google Scholar
Murphy, F. C., Michael, A., Robbins, T. W., & Sahakian, B. J. (2003). Neuropsychological impairment in patients with major depressive disorder: The effects of feedback on task performance. Psychological Medicine, 33(3): 455467.Google Scholar
Murphy, F. C., Rubinsztein, J. S., Michael, A., Rogers, R. D., Robbins, T. W., Paykel, E. S., & Sahakian, B. J. (2001). Decision-making cognition in mania and depression. Psychological Medicine, 31(4): 679693.Google Scholar
Olesen, J., Gustavsson, A., Svensson, M., Wittchen, H. U., & Jönsson, B., on behalf of the CDBE2010 study group and the European Brain Council (2012). The economic cost of brain disorders in Europe. European Journal of Neurology, 19: 155162.Google Scholar
Olvet, D. M., Burdick, K. E., & Cornblatt, B. A. (2012). Assessing the potential to use neurocognition to predict who is at risk for developing bipolar disorder: A review of the literature. Cognitive Neuropsychiatry, 18(1–2): 129145.Google Scholar
ONS (2005). Suicide rates in England and Wales, 2000 to 2003. Office for National Statistics (www.statistics.gov.uk).Google Scholar
Ormel, J., Koeter, M. J., van den Brink, W., & van de Willige, G. (1991). Recognition, management, and course of anxiety and depression in general practice. Archives of General Psychiatry, 48(8): 700706.Google Scholar
Owen, A. M., Evans, A. C., & Petrides, M. (1996). Evidence for a two-stage model of spatial working memory processing within the lateral frontal cortex: A positron emission tomography study. Cerebral Cortex, 6(1): 3138.CrossRefGoogle ScholarPubMed
Owen, A. M., Herrod, N. J., Menon, D. K., Clark, J. C., Downey, S. P. M. J., Carpenter, T. A., … Pickard, J. D. (1999). Redefining the functional organization of working memory processes within human lateral prefrontal cortex. European Journal of Neuroscience, 11(2): 567574.CrossRefGoogle ScholarPubMed
Owens, M., Goodyer, I. M., Wilkinson, P., Bhardwaj, A., Abbott, R., Croudace, T., … Sahakian, B. J. (2012). 5-HTTLPR and early childhood adversities moderate cognitive and emotional processing in adolescence. PLoS ONE, 7: e48482.Google Scholar
Owens, M., Herbert, J., Jones, P. B., Sahakian, B. J., Wilkinson, P. O., Dunn, V. J., … Goodyer, I. M. (2014). Elevated morning cortisol is a stratified population-level biomarker for major depression in boys only with high depressive symptoms. Proceedings of the National Academy of Sciences of the United States of America, 111(9): 36383643.CrossRefGoogle ScholarPubMed
Paykel, E. & Priest, R. (1992). Recognition and management of depression in general practice: Consensus statement. British Medical Journal, 305(6863): 11981202.CrossRefGoogle ScholarPubMed
Pulcu, E., Trotter, P., Thomas, E., McFarquhar, M., Juhasz, G., Sahakian, B., … Elliott, R. (2014). Temporal discounting in major depressive disorder. Psychological Medicine, 44: 18251834.Google Scholar
Robinson, O. J., Cools, R., & Sahakian, B. J. (2012). Tryptophan depletion disinhibits punishment but not reward prediction: Implications for resilience. Psychopharmacology (Berlin), 219(2): 599605.CrossRefGoogle Scholar
Robinson, O. J. & Sahakian, B. J. (2008). Recurrence in major depressive disorder: A neurocognitive perspective. Psychological Medicine, 38: 315318.CrossRefGoogle ScholarPubMed
Robinson, O. J. & Sahakian, B. J. (2013). Cognitive biomarkers in depression. In Lavretsky, H., Sajatovic, M., & Reynolds, C. (eds.), Late-Life Mood Disorders (pp. 606626). New York: Oxford University Press.Google Scholar
Rock, P. L., Roiser, J. P., Riedel, W. J., & Blackwell, A. D. (2014). Cognitive impairment in depression: A systematic review and meta-analysis. Psychological Medicine, 44: 20292040.Google Scholar
Roiser, J. P., Elliott, R., & Sahakian, B. J. (2012). Cognitive mechanisms of treatment in depression. Neuropsychopharmacology, 37(1): 117136.Google Scholar
Roiser, J. P. & Sahakian, B. J. (2013). Hot and cold cognition in depression. CNS Spectrums, 18(3): 139149.Google Scholar
Sahakian, B. J. (2014). What do experts think we should do to achieve brain health? Neuroscience and Biobehavioral Reviews, 43: 240258.Google Scholar
Scoriels, L., Barnett, J. H., Murray, G. K., Cherukuru, S., Fielding, M., Cheng, F., … Jones, P. B. (2011). Effects of modafinil on emotional processing in first episode psychosis. Biological Psychiatry, 69(5): 457464.Google Scholar
Scoriels, L., Jones, P. B., & Sahakian, B. J. (2013). Modafinil effects on cognition and emotion in schizophrenia and its neurochemical modulation in the brain. Neuropharmacology, 64: 168184.CrossRefGoogle ScholarPubMed
Tang, W., Liang, H., Lau, C., Tang, A., & Ungvari, G. S. (2013). Relationship between cognitive impairment and depressive symptoms in current ketamine users. Journal of Studies on Alcohol and Drugs, 74(3): 460468.Google Scholar
Taylor-Tavares, J., Clark, L., Furey, M., Williams, G., Sahakian, B., & Drevets, W. (2008). Neural basis of abnormal response to negative feedback in unmedicated mood disorders. NeuroImage, 42(3): 11181126.Google Scholar
Vos, T., Flaxman, A. D., Naghavi, M., Lozano, R., Michaud, C., Ezzati, M., … Memish, Z. A. (2012). Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: A systematic analysis for the Global Burden of Disease Study 2010. The Lancet, 380: 21632196.Google Scholar
Walsh, N. D., Williams, S. C. R., Brammer, M. J., Bullmore, E. T., Kim, J., Suckling, J., … Fu, C. H. Y. (2007). A longitudinal functional magnetic resonance imaging study of verbal working memory in depression after antidepressant therapy. Biological Psychiatry, 62(11): 12361243.Google Scholar
Yuan, K., Steedle, J., Shavelson, R., Alonzo, A., & Oppezzo, M. (2006). Working memory, fluid intelligence, and science learning. Educational Research Review, 1(2): 8398.Google Scholar
Zarate, C. A., Singh, J. B., Carlson, P. J., Brutsche, N. E., Ameli, R., Luckenbaugh, D. A., … Manji, H. K. (2006). A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Archives of General Psychiatry, 63(8): 856864.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×