Skip to main content Accessibility help
×
Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-06T11:57:18.268Z Has data issue: false hasContentIssue false

9 - Are cognitive deficits in major depressive disorder progressive?

from Part I - Clinical relevance of cognitive dysfunction in major depressive disorder

Published online by Cambridge University Press:  05 March 2016

Roger S. McIntyre
Affiliation:
University of Toronto
Danielle S. Cha
Affiliation:
University of Toronto
Get access
Type
Chapter
Information
Cognitive Impairment in Major Depressive Disorder
Clinical Relevance, Biological Substrates, and Treatment Opportunities
, pp. 110 - 124
Publisher: Cambridge University Press
Print publication year: 2016

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Airaksinen, E., Wahlin, A., Larsson, M., & Forsell, Y. (2006). Cognitive and social functioning in recovery from depression: Results from a population-based three-year follow-up. Journal of Affective Disorders, 96(1–2): 107110.Google Scholar
Austin, M. P., Mitchell, P., & Goodwin, G. M. (2001). Cognitive deficits in depression: Possible implications for functional neuropathology. British Journal of Psychiatry, 178(3): 200206.Google Scholar
Basso, M. R. & Bornstein, R. A. (1999). Relative memory deficits in recurrent versus first-episode major depression on a word-list learning task. Neuropsychology, 13(4): 557563.Google Scholar
Baune, B. T., Miller, R., McAfoose, J., Johnson, M., Quirk, F., & Mitchell, D. (2010). The role of cognitive impairment in general functioning in major depression. Psychiatry Research, 176(2–3): 183189.Google Scholar
Beats, B. C., Sahakian, B. J., & Levy, R. (1996). Cognitive performance in tests sensitive to frontal lobe dysfunction in the elderly depressed. Psychological Medicine, 26(3): 591603.Google Scholar
Behnken, A., Schöning, S., Gerss, J., Konrad, C., de Jong-Meyer, R., Zwanzger, P., & Arolt, V. (2010). Persistent non-verbal memory impairment in remitted major depression: Caused by encoding deficits? Journal of Affective Disorders, 122(1–2): 144148.Google Scholar
Bhardwaj, A., Wilkinson, P., Srivastava, C., & Sharma, M. (2010). Cognitive deficits in euthymic patients with recurrent depression. Journal of Nervous and Mental Disease, 198(7): 513515.Google Scholar
Biringer, E., Lundervold, A., Stordal, K., Mykletun, A., Egeland, J., Bottlender, R., & Lund, A. (2005). Executive function improvement upon remission of recurrent unipolar depression. European Archives of Psychiatry and Clinical Neuroscience, 255(6): 373380.Google Scholar
Boeker, H., Schulze, J., Richter, A., Nikisch, G., Schuepbach, D., & Grimm, S. (2012). Sustained cognitive impairments after clinical recovery of severe depression. Journal of Nervous and Mental Disease, 200(9): 773776.CrossRefGoogle ScholarPubMed
Bora, E., Harrison, B. J., Yucel, M., & Pantelis, C. (2013). Cognitive impairment in euthymic major depressive disorder: A meta-analysis. Psychological Medicine, 43(10): 20172026.CrossRefGoogle ScholarPubMed
Bremner, J. D., Vythilingam, M., Vermetten, E., Vaccarino, V., & Charney, D. S. (2004). Deficits in hippocampal and anterior cingulate functioning during verbal declarative memory encoding in midlife major depression. American Journal of Psychiatry, 161(4): 637645.CrossRefGoogle ScholarPubMed
Christensen, M. V., Kyvik, K. O., & Kessing, L. V. (2006). Cognitive function in unaffected twins discordant for affective disorder. Psychological Medicine, 36(8): 11191129.CrossRefGoogle ScholarPubMed
Clark, L., Chamberlain, S. R., & Sahakian, B. J. (2009). Neurocognitive mechanisms in depression: Implications for treatment. Annual Review of Neuroscience, 32: 5774.CrossRefGoogle ScholarPubMed
Colla, M., Kronenberg, G., Deuschle, M., Meichel, K., Hagen, T., Bohrer, M., & Heuser, I. (2007). Hippocampal volume reduction and HPA-system activity in major depression. Journal of Psychiatric Research, 41(7): 553560.Google Scholar
Czeh, B., Simon, M., Schmelting, B., Hiemke, C., & Fuchs, E. (2006). Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment. Neuropsychopharmacology, 31: 16161626.Google Scholar
Davidson, R. J., Pizzagalli, D., Nitschke, J. B., & Putnam, K. (2002). Depression: Perspectives from affective neuroscience. Annual Review of Psychology, 53: 545574.Google Scholar
Den Hartog, H. M., Derix, M. M. A., Van Bemmel, A. L., Kremer, B., & Jolles, J. (1999). Cognitive functioning in young and middle-aged unmedicated out-patients with major depression: Testing the effort and cognitive speed hypotheses. Psychological Medicine, 33(8): 14431451.Google Scholar
Douglas, K. M. & Porter, R. J. (2009). Longitudinal assessment of neuropsychological function in major depression. Australian and New Zealand Journal of Psychiatry, 43(12): 11051117.Google Scholar
Drevets, W. C. (2000). Neuroimaging studies of mood disorders. Biological Psychiatry, 48(8): 813829.Google Scholar
Duman, R. S. (2002). Pathophysiology of depression: The concept of synaptic plasticity. European Psychiatry, 17(Suppl. 3): 306310.Google Scholar
Frodl, T., Carballedo, A., Fagan, A. J., Lisiecka, D., Ferguson, Y., & Meaney, J. F. (2012). Effects of early-life adversity on white matter diffusivity changes in patients at risk for major depression. Journal of Psychiatry & Neuroscience, 37(1): 3745.Google Scholar
Gallagher, P., Robinson, L. J., Gray, J. M., Porter, R. J., & Young, A. H. (2007). Neurocognitive function following remission in major depressive disorder: Potential objective marker of response? Australian and New Zealand Journal of Psychiatry, 41(1): 5461.Google Scholar
Gorwood, P., Corruble, E., Falissard, B., & Goodwin, G. M. (2008). Toxic effects of depression on brain function: Impairment of delayed recall and the cumulative length of depressive disorder in a large sample of depressed outpatients. American Journal of Psychiatry, 165(6): 731739.Google Scholar
Gottesman, I. I. & Gould, T. D. (2003). The endophenotype concept in psychiatry: Etymology and strategic intentions. American Journal of Psychiatry, 160(4): 636645.Google Scholar
Grant, M. M., Thase, M. E., & Sweeney, J. A. (2001). Cognitive disturbance in outpatient depressed younger adults: Evidence of modest impairment. Biological Psychiatry, 50(1): 3543.Google Scholar
Hasselbalch, B. J., Knorr, U., Hasselbalch, S. G., Gade, A., & Kessing, L. V. (2013). The cumulative load of depressive illness is associated with cognitive function in the remitted state of unipolar depressive disorder. European Psychiatry, 28(6): 349355.CrossRefGoogle ScholarPubMed
Herrera-Guzman, I., Gudayol-Ferré, E., Herrera-Abarca, J. E., Herrera-Guzmán, D., Montelongo-Pedraza, P., Padrós Blázquez, F., … Guàrdia-Olmos, J. (2010). Major depressive disorder in recovery and neuropsychological functioning: Effects of selective serotonin reuptake inhibitor and dual inhibitor depression treatments on residual cognitive deficits in patients with major depressive disorder in recovery. Journal of Affective Disorders, 123(1–3): 341350.Google Scholar
Jaeger, J., Berns, S., Uzelac, S., & Davis-Conway, S. (2006). Neurocognitive deficits and disability in major depressive disorder. Psychiatry Research, 145(1): 3948.Google Scholar
Kendler, K. S., Thornton, L. M., & Gardner, C. O. (2000). Stressful life events and previous episodes in the etiology of major depression in women: An evaluation of the “kindling” hypothesis. American Journal of Psychiatry, 157(8): 12431251.Google Scholar
Kessing, L. V. (2012). Depression and the risk for dementia. Current Opinion in Psychiatry, 25(6): 457461.Google Scholar
Kessing, L. V., Andersen, P. K., Mortensen, P. B., & Bolwig, T. G. (1998). Recurrence in affective disorder. I: Case register study. British Journal of Psychiatry, 172(1): 2328.CrossRefGoogle ScholarPubMed
Krzysztof, K., Krzystanek, M., Janas-Kozik., M., Klasik, A., & Krupka-Matuszczyk, I. (2015). Impact of pharmacological and psychological treatment methods of depressive and anxiety disorders on cognitive functioning. Journal of Neural Transmission, 122(Suppl. 1): 101110.Google Scholar
Lampe, I. K., Sitskoorn, M. M., & Heeren, T. J. (2004). Effects of recurrent major depressive disorder on behavior and cognitive function in female depressed patients. Psychiatry Research, 125(2): 7379.Google Scholar
Lee, R. S., Hermens, D. F., Porter, M. A., & Redoblado-Hodge, M. A. (2012). A meta-analysis of cognitive deficits in first-episode major depressive disorder. Journal of Affective Disorders, 140(2): 113124.Google Scholar
Lorenzetti, V., Allen, N. B., Fornito, A., & Yucel, M. (2009). Structural brain abnormalities in major depressive disorder: A selective review of recent MRI studies. Journal of Affective Disorders, 117(1–2): 117.Google Scholar
MacQueen, G. M., Campbell, S., McEwen, B. S., Macdonald, K., Amano, S., Joffe, R. T., … Young, L. T. (2003). Course of illness, hippocampal function, and hippocampal volume in major depression. Proceedings of the National Academy of Sciences of the United States of America, 100(3): 13871392.CrossRefGoogle ScholarPubMed
MacQueen, G. M., Galway, T. M., Hay, J., Young, L. T., & Joffe, R. T. (2002). Recollection memory deficits in patients with major depressive disorder predicted by past depressions but not current mood state or treatment status. Psychological Medicine, 32(2): 251258.Google Scholar
Majer, M., Ising, M., Künzel, H., Binder, E. B., Holsboer, F., & Modell, S. (2004). Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders. Psychological Medicine, 34(8): 14531463.CrossRefGoogle ScholarPubMed
Mannie, Z. N., Barnes, J., Bristow, G. C., Harmer, C. J., & Cowen, P. J. (2009). Memory impairment in young women at increased risk of depression: Influence of cortisol and 5-HTT genotype. Psychological Medicine, 39(5): 757762.Google Scholar
Marazziti, D., Consoli, G., Picchetti, M., Carlini, M., & Faravelli, L. (2010). Cognitive impairment in major depression. European Journal of Pharmacology, 626(1): 8386.Google Scholar
McIntyre, R. S. (2013). Using measurement strategies to identify and monitor residual symptoms. Journal of Clinical Psychiatry, 74(Suppl. 2): 1418.Google Scholar
McIntyre, R. S., Cha, D. S., Soczynska, J. K., Woldeyohannes, H. O., Gallaugher, L. A., Kudlow, P., … Baskaran, A. (2013). Cognitive deficits and functional outcomes in major depressive disorder: Determinants, substrates, and treatment interventions. Depression and Anxiety, 30(6): 515527.Google Scholar
Monroe, S. M. & Harkness, K. L. (2005). Life stress, the “kindling” hypothesis, and the recurrence of depression: Considerations from a life stress perspective. Psychological Review, 112(2): 417445.Google Scholar
Nagane, A., Baba, H., Nakano, Y., Maeshima, H., Hukatsu, M., Ozawa, A., … Arai, H. (2014). Comparative study of cognitive impairment between medicated and medication-free patients with remitted major depression: Class-specific influence by tricyclic antidepressants and newer antidepressants. Psychiatry Research, 218(1–2): 101105.Google Scholar
Neu, P., Bajbouj, M., Schilling, A., Godemann, F., Berman, R. M., & Schlattmann, P. (2005). Cognitive function over the treatment course of depression in middle-aged patients: Correlation with brain MRI signal hyperintensities. Journal of Psychiatric Research, 39(2): 129135.Google Scholar
Paelecke-Habermann, Y., Pohl, J., & Leplow, B. (2005). Attention and executive functions in remitted major depression patients. Journal of Affective Disorders, 89(1–3): 125135.CrossRefGoogle ScholarPubMed
Pedersen, A., Küppers, K., Behnken, A., Kroker, K., Schöning, S., Baune, B. T., … Suslow, T. (2009).Implicit and explicit procedural learning in patients recently remitted from severe major depression. Psychiatry Research, 169(1): 16.Google Scholar
Porter, R. J., Gallagher, P., Thompson, J. M., & Young, A. H. (2003). Neurocognitive impairment in drug-free patients with major depressive disorder. British Journal of Psychiatry, 182: 214220.Google Scholar
Preiss, M., Kucerova, H., Lukavsky, J., Stepankova, H., Sos, P., & Kawaciukova, R. (2009). Cognitive deficits in the euthymic phase of unipolar depression. Psychiatry Research, 169(3): 235239.Google Scholar
Purcell, R., Maruff, P., Kyrios, M., & Pantelis, C. (1997). Neuropsychological function in young patients with unipolar major depression. Psychological Medicine, 27(6): 12771285.Google Scholar
Rapp, M. A., Dahlman, K., Sano, M., Grossman, H. T., Haroutunian, V., & Gorman, J. M. (2005). Neuropsychological differences between late-onset and recurrent geriatric major depression. American Journal of Psychiatry, 162(4): 691698.Google Scholar
Reppermund, S., Ising, M., Lucae, S., & Zihl, J. (2009). Cognitive impairment in unipolar depression is persistent and non-specific: Further evidence for the final common pathway disorder hypothesis. Psychological Medicine, 39(4): 603614.Google Scholar
Rock, P. L., Roiser, J. P., Riedel, W. J., & Blackwell, A. D. (2014). Cognitive impairment in depression: A systematic review and meta-analysis. Psychological Medicine, 44(10): 20292040.Google Scholar
Sheline, Y. I., Gado, M. H., & Kraemer, H. C. (2003). Untreated depression and hippocampal volume loss. American Journal of Psychiatry, 160(8): 15161518.Google Scholar
Sheline, Y. I., Sanghavi, M., Mintun, M. A., & Gado, M. H. (1999). Depression duration but not age predicts hippocampal volume loss in medically healthy women with recurrent major depression. Journal of Neuroscience, 19(12): 50345043.Google Scholar
Trivedi, M. H. & Greer, T. L. (2014). Cognitive dysfunction in unipolar depression: Implications for treatment. Journal of Affective Disorders, 152–154: 1927.Google Scholar
Vythilingam, M., Vermetten, E., Anderson, G. M., Luckenbaugh, D., Anderson, E. R., Snow, J., … Bremner, J. D. (2004). Hippocampal volume, memory, and cortisol status in major depressive disorder: Effects of treatment. Biological Psychiatry, 56(2): 101112.Google Scholar
Weiland-Fiedler, P., Erickson, K., Waldeck, T., Luckenbaugh, D. A., Pike, D., Bonne, O., … Neumeister, A. (2004). Evidence for continuing neuropsychological impairments in depression. Journal of Affective Disorders, 82(2): 253258.Google Scholar
Weingartner, H., Cohen, R. M., Murphy, D. L., Martello, J., & Gerdt, C. (1981). Cognitive processes in depression. Archives of General Psychiatry, 38(1): 4247.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×