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Chapter 19 - How to Analyze a Study

Published online by Cambridge University Press:  20 January 2023

S. Nassir Ghaemi
S. Nassir Ghaemi
Affiliation:
Tufts University School of Medicine, Boston
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Summary

The most common method of assessing maintenance efficacy in psychiatry is the randomized discontinuation (enriched) trial, which produces false positive results, leading to mistaken belief in efficacy of many agents. This chapter provides a critique of that trial design and its harmful impact on clinical practice for antidepressants and antipsychotics.

Keywords

maintenance efficacyrandomized discontinuationenriched trials
Type
Chapter
Information
A Clinician's Guide to Statistics in Mental Health , pp. 139 - 144
Publisher: Cambridge University Press
Print publication year: 2023

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  • How to Analyze a Study
  • S. Nassir Ghaemi, Tufts University School of Medicine, Boston
  • Book: A Clinician's Guide to Statistics in Mental Health
  • Online publication: 20 January 2023
  • Chapter DOI: https://doi.org/10.1017/9781108887526.020
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  • How to Analyze a Study
  • S. Nassir Ghaemi, Tufts University School of Medicine, Boston
  • Book: A Clinician's Guide to Statistics in Mental Health
  • Online publication: 20 January 2023
  • Chapter DOI: https://doi.org/10.1017/9781108887526.020
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • How to Analyze a Study
  • S. Nassir Ghaemi, Tufts University School of Medicine, Boston
  • Book: A Clinician's Guide to Statistics in Mental Health
  • Online publication: 20 January 2023
  • Chapter DOI: https://doi.org/10.1017/9781108887526.020
Available formats
×