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Chapter 12 - Mood Disorders and Comorbid Substance Use Disorders

Published online by Cambridge University Press:  16 May 2024

Allan Young
Affiliation:
Institute of Psychiatry, King's College London
Marsal Sanches
Affiliation:
Baylor College of Medicine, Texas
Jair C. Soares
Affiliation:
McGovern Medical School, The University of Texas
Mario Juruena
Affiliation:
King's College London
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Summary

Substance use disorders commonly co-occur with mood disorders (major depression, bipolar disorder) and may be due to the direct effects of illicit substances, such as intoxication and withdrawal, or due to effects stemming from chronic use, including substance-induced mood disorders. Self-medication of mood disorders with legal or illicit substances is highly prevalent. Careful assessment of patients is necessary to determine whether a co-occurring disorder is due to substance use or a separate diagnosis that requires independent treatment. Many depressive symptoms may resolve with treatment of the substance use disorder. Independent mood disorders can be treated with behavioral therapy and standard pharmacological therapy. Some mood disorder medications are also effective for substance use disorders. Some substances that have historically been used recreationally are being studied as possible treatments for mood disorders.

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Publisher: Cambridge University Press
Print publication year: 2024

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