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Chapter 20 - An Update on the Treatment of Manic and Hypomanic States

Published online by Cambridge University Press:  16 May 2024

By
Sameer Jauhar  and
Sui Liem Alexandre Wong
Edited by
Allan Young ,
Marsal Sanches ,
Jair C. Soares  and
Mario Juruena
Allan Young
Affiliation:
Institute of Psychiatry, King's College London
Marsal Sanches
Affiliation:
Baylor College of Medicine, Texas
Jair C. Soares
Affiliation:
McGovern Medical School, The University of Texas
Mario Juruena
Affiliation:
King's College London
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Summary

Acute mania is a medical emergency and requires assiduous treatment to prevent significant risks to the individual, as well as effects on aspects of their psychosocial functioning. Hypomania has a similar clinical profile, with the absence of psychotic symptoms and disruption of functioning being the main factors differentiating it from mania. In this chapter we cover the key points in regard to clinical signs and management of mania and hypomania, predominantly focusing on pharmacological treatments. A number of national and international guidelines have covered this in depth, and we summarise their findings in this chapter. First-, second-, and third-line medication options for the acute phases are reviewed, while we also discuss combination strategies to address specific symptoms (e.g., agitation) and maintenance treatments aiming at relapse prevention and functional recovery.

Keywords

maniahypomaniabipolar disorderpsychopharmacologyacute treatmentmaintenance
Type
Chapter
Information
Clinical Textbook of Mood Disorders , pp. 206 - 212
Publisher: Cambridge University Press
Print publication year: 2024

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