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Chapter 22 - Magnetic resonance spectroscopy in adult neoplasia

from Section 3 - Adult neoplasia

Published online by Cambridge University Press:  05 March 2013

By
Tracy Richmond McKnight  and
Adam D. Waldman
Edited by
Jonathan H. Gillard ,
Adam D. Waldman  and
Peter B. Barker
Jonathan H. Gillard
Affiliation:
University of Cambridge
Adam D. Waldman
Affiliation:
Imperial College London
Peter B. Barker
Affiliation:
The Johns Hopkins University School of Medicine
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Summary

Introduction

The socioeconomic impact of adult primary brain neoplasms is disproportionate to their incidence; they often affect young adults, cause significant morbidity, and are usually ultimately fatal. Moreover, advances in treatment of primary malignancies outside the CNS has led to more aggressive clinical management of brain metastases.

Reliable characterization of intracranial masses is, therefore, essential for rational clinical management: in initial diagnosis and prognosis, stratification and planning of therapy for individual patients, and evaluating outcome with established and novel treatment regimens.

The relatively high risk of performing invasive procedures in the brain places particular emphasis on neuroimaging in the evaluation of brain masses. Conventional structural MRI and computed tomography (CT) are widely used in clinical practice but provide limited biological specificity and diagnostic and prognostic information. Non-invasive physiological imaging techniques that augment the information available from structural imaging and inform clinical management are clearly desirable.

Type
Chapter
Information
Clinical MR Neuroimaging
Physiological and Functional Techniques
 , pp. 295 - 320
Publisher: Cambridge University Press
Print publication year: 2009

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To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

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