Book contents
- Frontmatter
- Dedication
- Contents
- List of Contributors
- Preface
- Part I Clinical syndromes: general
- Part II Clinical syndromes: head and neck
- Part III Clinical syndromes: eye
- Part IV Clinical syndromes: skin and lymph nodes
- Part V Clinical syndromes: respiratory tract
- Part VI Clinical syndromes: heart and blood vessels
- Part VII Clinical syndromes: gastrointestinal tract, liver, and abdomen
- Part VIII Clinical syndromes: genitourinary tract
- Part IX Clinical syndromes: musculoskeletal system
- Part X Clinical syndromes: neurologic system
- Part XI The susceptible host
- Part XII HIV
- Part XIII Nosocomial infection
- Part XIV Infections related to surgery and trauma
- Part XV Prevention of infection
- Part XVI Travel and recreation
- Part XVII Bioterrorism
- Part XVIII Specific organisms: bacteria
- 123 Actinomycosis
- 124 Anaerobic infections
- 125 Anthrax and other Bacillus species
- 126 Bartonella bacilliformis
- 127 Cat scratch disease and other Bartonella infections
- 128 Bordetella
- 129 Branhamella–Moraxella
- 130 Brucellosis
- 131 Campylobacter
- 132 Clostridium
- 133 Corynebacteria
- 134 Enterobacteriaceae
- 135 Enterococcus
- 136 Erysipelothrix
- 137 HACEK
- 138 Helicobacter pylori
- 139 Gonococcus: Neisseria gonorrhoeae
- 140 Haemophilus
- 141 Legionellosis
- 142 Leprosy
- 143 Meningococcus and miscellaneous neisseriae
- 144 Listeria
- 145 Nocardia
- 146 Pasteurella multocida
- 147 Pneumococcus
- 148 Pseudomonas, Stenotrophomonas, and Burkholderia
- 149 Rat-bite fevers
- 150 Salmonella
- 151 Staphylococcus
- 152 Streptococcus groups A, B, C, D, and G
- 153 Viridans streptococci
- 154 Poststreptococcal immunologic complications
- 155 Shigella
- 156 Tularemia
- 157 Tuberculosis
- 158 Nontuberculous mycobacteria
- 159 Vibrios
- 160 Yersinia
- 161 Miscellaneous gram-positive organisms
- 162 Miscellaneous gram-negative organisms
- Part XIX Specific organisms: spirochetes
- Part XX Specific organisms: Mycoplasma and Chlamydia
- Part XXI Specific organisms: Rickettsia, Ehrlichia, and Anaplasma
- Part XXII Specific organisms: fungi
- Part XXIII Specific organisms: viruses
- Part XXIV Specific organisms: parasites
- Part XXV Antimicrobial therapy: general considerations
- Index
- References
127 - Cat scratch disease and other Bartonella infections
from Part XVIII - Specific organisms: bacteria
Published online by Cambridge University Press: 05 April 2015
- Frontmatter
- Dedication
- Contents
- List of Contributors
- Preface
- Part I Clinical syndromes: general
- Part II Clinical syndromes: head and neck
- Part III Clinical syndromes: eye
- Part IV Clinical syndromes: skin and lymph nodes
- Part V Clinical syndromes: respiratory tract
- Part VI Clinical syndromes: heart and blood vessels
- Part VII Clinical syndromes: gastrointestinal tract, liver, and abdomen
- Part VIII Clinical syndromes: genitourinary tract
- Part IX Clinical syndromes: musculoskeletal system
- Part X Clinical syndromes: neurologic system
- Part XI The susceptible host
- Part XII HIV
- Part XIII Nosocomial infection
- Part XIV Infections related to surgery and trauma
- Part XV Prevention of infection
- Part XVI Travel and recreation
- Part XVII Bioterrorism
- Part XVIII Specific organisms: bacteria
- 123 Actinomycosis
- 124 Anaerobic infections
- 125 Anthrax and other Bacillus species
- 126 Bartonella bacilliformis
- 127 Cat scratch disease and other Bartonella infections
- 128 Bordetella
- 129 Branhamella–Moraxella
- 130 Brucellosis
- 131 Campylobacter
- 132 Clostridium
- 133 Corynebacteria
- 134 Enterobacteriaceae
- 135 Enterococcus
- 136 Erysipelothrix
- 137 HACEK
- 138 Helicobacter pylori
- 139 Gonococcus: Neisseria gonorrhoeae
- 140 Haemophilus
- 141 Legionellosis
- 142 Leprosy
- 143 Meningococcus and miscellaneous neisseriae
- 144 Listeria
- 145 Nocardia
- 146 Pasteurella multocida
- 147 Pneumococcus
- 148 Pseudomonas, Stenotrophomonas, and Burkholderia
- 149 Rat-bite fevers
- 150 Salmonella
- 151 Staphylococcus
- 152 Streptococcus groups A, B, C, D, and G
- 153 Viridans streptococci
- 154 Poststreptococcal immunologic complications
- 155 Shigella
- 156 Tularemia
- 157 Tuberculosis
- 158 Nontuberculous mycobacteria
- 159 Vibrios
- 160 Yersinia
- 161 Miscellaneous gram-positive organisms
- 162 Miscellaneous gram-negative organisms
- Part XIX Specific organisms: spirochetes
- Part XX Specific organisms: Mycoplasma and Chlamydia
- Part XXI Specific organisms: Rickettsia, Ehrlichia, and Anaplasma
- Part XXII Specific organisms: fungi
- Part XXIII Specific organisms: viruses
- Part XXIV Specific organisms: parasites
- Part XXV Antimicrobial therapy: general considerations
- Index
- References
Summary
Introduction
Cat scratch disease (CSD) was first described in 1950 by Rene Debré as “La Maladie de Griff de Chat.” Its cause remained a mystery until the late twentieth century, when amplification and sequencing of 16S rRNA genes was introduced as a method of identifying organisms that had not been successfully cultured. In 1992, David Relman and co-workers used this technique to identify the agent of CSD, and bacillary angiomatosis and parenchymal bacillary peliosis (BAP). He found that the causative organism was a small gram-negative coccobacillus closely related to the agents causing trench fever, brucellosis, and crown gall disease in plants (Agrobacterium tumefaciens).
The organism was first named Rochalimaea henselae, and was subsequently grouped within the family Bartonellaceae, along with a number of other organisms, including the agents of trench fever, Bartonella quintana (formerly Rochalimaea quintana). Bartonella bacilliformis, the agent of acute and chronic Carrión's disease is a related ancestor of modern members of the family Bartonellaceae. Recent reports suggest that similar clinical syndromes in the Andean highlands may also be caused by Bartonella rochalimae and possibly Candidatus Bartonella ancashi 20.0. These organisms, and probably others of the genus, share the ability to invade vascular endothelial cells, bone marrow erythroblasts, and mature erythrocytes. They also share the ability to induce macrophage-mediated secretion of proinflammatory cytokines (notably interleukin-10 [IL-10]) andvascular endothelial cell growth factor (VEGF) and the ability to suppress vascular endothelial cell apoptosis. These virulence factors give them the ability to disseminate within the host, causing proliferative vascular lesions and prolonged bacteremia in humans and mammalian reservoirs.
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- Information
- Clinical Infectious Disease , pp. 853 - 858Publisher: Cambridge University PressPrint publication year: 2015
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