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Chapter 15 - Spinal Muscular Atrophy

Published online by Cambridge University Press:  30 November 2019

Adam C. Adler
Affiliation:
Texas Children's Hospital
Arvind Chandrakantan
Affiliation:
Texas Children's Hospital
Ronald S. Litman
Affiliation:
The Children's Hospital of Philadelphia
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Summary

This chapter provides a brief review of Spinal muscular atrophy and its three subtypes. The newly available treatment Nusinersen, (Spinraza) is discussed as are the anesthetic concerns related to this medically complex patient population.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2019

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References

Suggested Reading

Graham, RJ, Athiraman, U, Laubach, AE, et al. Anesthesia and perioperative medical management of children with spinal muscular atrophy. Paediatr Anaesth. 2009 Nov;19(11):1054–63. PMID: 19558636.CrossRefGoogle ScholarPubMed
Islander, G. Anesthesia and spinal muscle atrophy. Paediatr Anaesth. 2013;23(9):804–16. PMID: 23601145.CrossRefGoogle ScholarPubMed
Mesfin, A, Sponseller, PD, Leet, AI. Spinal muscular atrophy: manifestations and management. J Am Acad Orthop Surg. 2012;20(6):393401. PMID: 22661569.CrossRefGoogle ScholarPubMed

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