Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-17T16:11:00.226Z Has data issue: false hasContentIssue false

Chapter 15 - Spinal Muscular Atrophy

Published online by Cambridge University Press:  30 November 2019

By
Jamie W. Sinton  and
William D. Ryan
Edited by
Adam C. Adler ,
Arvind Chandrakantan  and
Ronald S. Litman
Adam C. Adler
Affiliation:
Texas Children's Hospital
Arvind Chandrakantan
Affiliation:
Texas Children's Hospital
Ronald S. Litman
Affiliation:
The Children's Hospital of Philadelphia
Get access

Summary

This chapter provides a brief review of Spinal muscular atrophy and its three subtypes. The newly available treatment Nusinersen, (Spinraza) is discussed as are the anesthetic concerns related to this medically complex patient population.

Keywords

Spinal muscular atrophymotor weaknessanterior hornWerdnig-Hoffmannjuvenile spinal muscular atrophyWohlfart-Kugelberg-Welander syndromenusinersenSpinraza
Type
Chapter
Information
Case Studies in Pediatric Anesthesia , pp. 68 - 69
Publisher: Cambridge University Press
Print publication year: 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Suggested Reading

Graham, RJ, Athiraman, U, Laubach, AE, et al. Anesthesia and perioperative medical management of children with spinal muscular atrophy. Paediatr Anaesth. 2009 Nov;19(11):1054–63. PMID: 19558636.CrossRefGoogle ScholarPubMed
Islander, G. Anesthesia and spinal muscle atrophy. Paediatr Anaesth. 2013;23(9):804–16. PMID: 23601145.CrossRefGoogle ScholarPubMed
Mesfin, A, Sponseller, PD, Leet, AI. Spinal muscular atrophy: manifestations and management. J Am Acad Orthop Surg. 2012;20(6):393–401. PMID: 22661569.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×