Book contents
- Capnography
- Capnography
- Copyright page
- Contents
- Contributors
- Preface
- Commonly used abbreviations
- 1 Clinical perspectives
- 1 Ventilation
- 2 Ventilation Capnography and respiratory assessment outside of the operating room
- 3 Airway management in the out-of-hospital setting
- 4 Airway management in the hospital setting
- 5 Airway management in the operating room
- 6 Capnography during anesthesia
- 7 Monitoring during mechanical ventilation
- 8 Capnography during transport of patients (inter/intrahospital)
- 9 Capnography as a guide to ventilation in the field
- 10 Neonatal monitoring
- 11 Capnography in sleep medicine
- 12 Conscious sedation
- 13 Capnometry monitoring in high- and low-pressure environments
- 14 Biofeedback
- 15 Capnography in non-invasive positive pressure ventilation
- 16 End-tidal carbon dioxide monitoring in postoperative ventilator weaning
- 17 Optimizing the use of mechanical ventilation and minimizing its requirement with capnography
- 18 Volumetric capnography for monitoring lung recruitment and PEEP titration
- 19 Capnography and adjuncts of mechanical ventilation
- 20 Cardiopulmonary resuscitation
- 21 Capnography and pulmonary embolism
- 22 Non-invasive cardiac output via pulmonary blood flow
- 23 PaCO2, PetCO2, and gradient
- 24 The physiologic basis for capnometric monitoring in shock
- 25 Carbon dioxide production, metabolism, and anesthesia
- 26 Tissue- and organ-specific effects of carbon dioxide
- 27 Atmospheric monitoring outside the healthcare environment and within enclosed environments: a historical perspective
- 28 Capnography in veterinary medicine
- 29 Carbon dioxide pathophysiology
- 30 Acid–base balance and diagnosis of disorders
- 31 Ventilation/perfusion abnormalities and capnography
- 32 Capnographic measures
- 33 Improving the analysis of volumetric capnograms
- 34 Capnography and the single-path model applied to cardiac output recovery and airway structure and function
- 35 Carbon dioxide and the control of breathing: a quantitative approach
- 36 Technical specifications and standards
- 37 Carbon dioxide measurement
- 38 Gas flow measurement
- 39 Combining flow and carbon dioxide
- 40 Brief history of time and volumetric capnography
- 41 The first years of clinical capnography
- 42 The early days of volumetric capnography
- Appendix: Patterns of time-based capnograms
- Index
35 - Carbon dioxide and the control of breathing: a quantitative approach
from 1 - Ventilation
Published online by Cambridge University Press: 05 August 2011
Book contents
- Capnography
- Capnography
- Copyright page
- Contents
- Contributors
- Preface
- Commonly used abbreviations
- 1 Clinical perspectives
- 1 Ventilation
- 2 Ventilation Capnography and respiratory assessment outside of the operating room
- 3 Airway management in the out-of-hospital setting
- 4 Airway management in the hospital setting
- 5 Airway management in the operating room
- 6 Capnography during anesthesia
- 7 Monitoring during mechanical ventilation
- 8 Capnography during transport of patients (inter/intrahospital)
- 9 Capnography as a guide to ventilation in the field
- 10 Neonatal monitoring
- 11 Capnography in sleep medicine
- 12 Conscious sedation
- 13 Capnometry monitoring in high- and low-pressure environments
- 14 Biofeedback
- 15 Capnography in non-invasive positive pressure ventilation
- 16 End-tidal carbon dioxide monitoring in postoperative ventilator weaning
- 17 Optimizing the use of mechanical ventilation and minimizing its requirement with capnography
- 18 Volumetric capnography for monitoring lung recruitment and PEEP titration
- 19 Capnography and adjuncts of mechanical ventilation
- 20 Cardiopulmonary resuscitation
- 21 Capnography and pulmonary embolism
- 22 Non-invasive cardiac output via pulmonary blood flow
- 23 PaCO2, PetCO2, and gradient
- 24 The physiologic basis for capnometric monitoring in shock
- 25 Carbon dioxide production, metabolism, and anesthesia
- 26 Tissue- and organ-specific effects of carbon dioxide
- 27 Atmospheric monitoring outside the healthcare environment and within enclosed environments: a historical perspective
- 28 Capnography in veterinary medicine
- 29 Carbon dioxide pathophysiology
- 30 Acid–base balance and diagnosis of disorders
- 31 Ventilation/perfusion abnormalities and capnography
- 32 Capnographic measures
- 33 Improving the analysis of volumetric capnograms
- 34 Capnography and the single-path model applied to cardiac output recovery and airway structure and function
- 35 Carbon dioxide and the control of breathing: a quantitative approach
- 36 Technical specifications and standards
- 37 Carbon dioxide measurement
- 38 Gas flow measurement
- 39 Combining flow and carbon dioxide
- 40 Brief history of time and volumetric capnography
- 41 The first years of clinical capnography
- 42 The early days of volumetric capnography
- Appendix: Patterns of time-based capnograms
- Index
Summary
This chapter presents an additional perspective that emphasizes the integrative and dynamic aspects of ventilatory control specifically with respect to CO2. The dynamic factors affecting the chemoreflex control of ventilation are multifaceted, and their interactions can easily lead to complex behavior. A quantitative approach that employs mathematical modeling as a tool enables one to sort out which factor contributes to which facet of the observed behavior. The evidence to date suggests that input from the central and peripheral chemoreceptors or from the higher centers is required to produce oscillatory activity in the brainstem respiratory neurons and network. An alternative approach for assessing dynamic chemoresponsiveness involves the careful monitoring of VE and PETCO2 following natural perturbations to the respiratory control system. The more complex nature of the stimuli and the resulting responses in ventilation necessitate the application of computational methodologies derived from the realm of signal and system analysis.
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- Capnography , pp. 360 - 370Publisher: Cambridge University PressPrint publication year: 2011