Book contents
- Frontmatter
- Contents
- Contributors
- Overview: Biology Is the Foundation of Therapy
- PART I BASIC RESEARCH
- PART II CLINICAL RESEARCH
- 23 Introduction to Clinical Research
- 24 Sarcoma
- 25 Neuroblastoma
- 26 Retinoblastoma
- 27 Primary Brain Tumors and Cerebral Metastases
- 28 Head and Neck Cancer Metastasis
- 29 Cutaneous Melanoma: Therapeutic Approaches for Metastatic Disease
- 30 Gastric Cancer Metastasis
- 31 Metastatic Pancreatic Cancer
- 32 Metastasis of Primary Liver Cancer
- 33 Advances in Management of Metastatic Colorectal Cancer
- 34 Lung Cancer Metastasis
- 35 Metastatic Thyroid Cancer: Evaluation and Treatment
- 36 Metastatic Renal Cell Carcinoma
- 37 Bladder Cancer
- 38 Bone Complications of Myeloma and Lymphoma
- 39 Breast Metastasis
- 40 Gynecologic Malignancies
- 41 Prostate Cancer Metastasis: Thoughts on Biology and Therapeutics
- 42 The Biology and Treatment of Metastatic Testicular Cancer
- 43 Applications of Proteomics to Metastasis Diagnosis and Individualized Therapy
- 44 Critical Issues of Research on Circulating and Disseminated Tumor Cells in Cancer Patients
- 45 Lymphatic Mapping and Sentinel Lymph Node Biopsy
- 46 Molecular Imaging and Metastasis
- 47 Preserving Bone Health in Malignancy and Complications of Bone Metastases
- 48 Role of Platelets and Thrombin in Metastasis
- THERAPIES
- 49 Cancer Nanotechnology Offers Great Promise for Cancer Research and Therapy
- 50 Metronomic Chemotherapy for Treatment of Metastatic Disease: From Preclinical Research to Clinical Trials
- 51 Immunotherapy
- 52 Discovery and Development of Drugs Targeting Tumor Invasion and Metastasis
- 53 The Role of Radiotherapy in the Treatment of Metastatic Disease
- 54 Prospects for Clinical Trials of Metastasis Inhibitors
- Index
- References
49 - Cancer Nanotechnology Offers Great Promise for Cancer Research and Therapy
from THERAPIES
Published online by Cambridge University Press: 05 June 2012
- Frontmatter
- Contents
- Contributors
- Overview: Biology Is the Foundation of Therapy
- PART I BASIC RESEARCH
- PART II CLINICAL RESEARCH
- 23 Introduction to Clinical Research
- 24 Sarcoma
- 25 Neuroblastoma
- 26 Retinoblastoma
- 27 Primary Brain Tumors and Cerebral Metastases
- 28 Head and Neck Cancer Metastasis
- 29 Cutaneous Melanoma: Therapeutic Approaches for Metastatic Disease
- 30 Gastric Cancer Metastasis
- 31 Metastatic Pancreatic Cancer
- 32 Metastasis of Primary Liver Cancer
- 33 Advances in Management of Metastatic Colorectal Cancer
- 34 Lung Cancer Metastasis
- 35 Metastatic Thyroid Cancer: Evaluation and Treatment
- 36 Metastatic Renal Cell Carcinoma
- 37 Bladder Cancer
- 38 Bone Complications of Myeloma and Lymphoma
- 39 Breast Metastasis
- 40 Gynecologic Malignancies
- 41 Prostate Cancer Metastasis: Thoughts on Biology and Therapeutics
- 42 The Biology and Treatment of Metastatic Testicular Cancer
- 43 Applications of Proteomics to Metastasis Diagnosis and Individualized Therapy
- 44 Critical Issues of Research on Circulating and Disseminated Tumor Cells in Cancer Patients
- 45 Lymphatic Mapping and Sentinel Lymph Node Biopsy
- 46 Molecular Imaging and Metastasis
- 47 Preserving Bone Health in Malignancy and Complications of Bone Metastases
- 48 Role of Platelets and Thrombin in Metastasis
- THERAPIES
- 49 Cancer Nanotechnology Offers Great Promise for Cancer Research and Therapy
- 50 Metronomic Chemotherapy for Treatment of Metastatic Disease: From Preclinical Research to Clinical Trials
- 51 Immunotherapy
- 52 Discovery and Development of Drugs Targeting Tumor Invasion and Metastasis
- 53 The Role of Radiotherapy in the Treatment of Metastatic Disease
- 54 Prospects for Clinical Trials of Metastasis Inhibitors
- Index
- References
Summary
NANOTECHNOLOGY
Nanotechnology, sometimes shortened to “nanotech,” refers to a field of applied science whose goal is to control matter on an atomic and molecular scale. Nanotechnology is an extremely diverse and multidisciplinary field, ranging from novel extensions of conventional-device physics to completely new approaches based on molecular self-assembly and to developing new materials with sizes ranging from 0.1 to hundreds of nanometers. A nanometer is one-billionth of a meter (10−9 m), which is about ten times the size of the smallest atom, hydrogen, and approximately 1/80,000 the width of a human hair. As Richard Feynman's famous statement that “there is plenty of room at the bottom” [1] portends, nanotechnology has the potential to create new materials and devices in the nanoscale range with wide-ranging applications in medicine, electronics, and energy production.
The human cell is 10,000 to 20,000 nm in diameter. Cellular proliferation and replication operate at the nanometer scale, thus demonstrating the need to translate molecular-based science into machines or devices matching the size of molecules in biology. There are several advantages to designing devices of this size in every industry imaginable. The computer chip industry has vastly expanded computational speed by decreasing the size and increasing the number of transistors per chip. The reduction in the size of key elements, down to about 100 nm, is possible because of improvements in photolithography that characteristically reduce the cost of production.
- Type
- Chapter
- Information
- Cancer MetastasisBiologic Basis and Therapeutics, pp. 563 - 572Publisher: Cambridge University PressPrint publication year: 2011