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VIII.88 - Measles

from Part VIII - Major Human Diseases Past and Present

Published online by Cambridge University Press:  28 March 2008

Kenneth F. Kiple
Affiliation:
Bowling Green State University, Ohio
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Summary

Measles (rubeola; hard measles; red measles; 9-day measles; morbilli) is a common, acute, viral infectious disease, principally of children, with worldwide distribution, that is clinically characterized by fever and a typical red, blotchy rash combined with cough, coryza, or conjunctivitis. It is a vaccine-preventable disease, and its vaccine is one of the vaccines included in the Expanded Programme on Immunization (EPI) of the World Health Organization (WHO). The disease is known by many local names throughout the world.

Etiology and Epidemiology

Measles is caused by a virus, which is in the genus Morbillivirus of the family Paramyxoviridae. Although the virus does not survive drying on a surface, it can survive drying in microdroplets in the air.

Measles is one of the most highly communicable diseases, transmitted by contact of susceptible individuals with the nose and throat secretions of infected persons, primarily by droplet spread. Infection also occurs by direct contact, and by indirect contact through freshly soiled articles and airborne transmission. There is no reservoir for measles other than human beings, which means that a continuous chain of susceptible contacts is necessary to sustain transmission. The period of communicability is from slightly before the beginning of the prodromal phase of the disease to 4 days after the start of the rash. There is no carrier state. Measles has an incubation period from time of exposure to onset of fever of about 10 days with a range from 8 to 13 days. The incubation period from time of exposure to rash onset is about 14 days.

In populated areas with no or low vaccination coverage, measles is primarily an endemic disease of children, with epidemics occurring every 2 to 5 years. In such areas, the greatest incidence is in children under 2 years of age. Epidemic measles has a winter-spring seasonality in temperate climates and a less marked hot-dry seasonality in equatorial regions.

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Publisher: Cambridge University Press
Print publication year: 1993

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References

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  • Measles
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.150
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  • Measles
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.150
Available formats
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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Measles
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.150
Available formats
×