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27 - Psychology and Human Rights in the Age of Genomics and Neuroscience

from Part III - Contemporary Issues in Psychology and Human Rights

Published online by Cambridge University Press:  02 October 2020

Neal S. Rubin
Affiliation:
Adler University
Roseanne L. Flores
Affiliation:
Hunter College, City University of New York
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Summary

Psychology, which has branched out of philosophy and has deep roots in biology, is experiencing a sea change in behavioral analysis that is backed by our new understanding of the multifactorial influences of genes and their interaction with the environment, through the agency of genomewide association studies (GWAS) and emerging neurotechnologies. Two specific demands and challenges relating to this development in the human rights domain are first, to reconceptualize the principles of existing human rights frameworks in light of developments in genomics and neuroscience and second, to create new human rights standards given the novel prescriptions highlighted by contemporary scientific investigations. Advances in genomics and neuroscience compel psychologists to redefine their role in protecting the human rights of patients through their ethical codes as well as human rights norms while addressing new challenges. Against this backdrop, this chapter is an attempt to explain underlying transformations in the field of human genomics and neuroscience and analyze their impact on psychology and human rights. Specifically, it covers the changing paradigm of psychology, implications of human genomics for psychology, the interface of psychology and human rights, and the impact of genomics and neurosciences on this interface.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2020

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References

Abadi, A., Alyass, A., du Pont, S. R., Bolker, B., Singh, P., Mohan, V., … Anand, S. S. (2017). Penetrance of polygenic obesity susceptibility loci across the body mass index distribution. American Journal of Human Genetics, 101(6), 925–938.Google Scholar
Allan, A. (2013). Are human rights redundant in the ethical codes of psychologists? Ethics and Behaviour, 23(4), 251–265. https://ro.ecu.edu.au/cgi/viewcontent.cgi?article=1801&context=ecuworks2013Google Scholar
Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., … Patsopoulos, N. A. (2018). Analysis of shared heritability in common disorders of the brain. Science, 360(6395), eaap8757.Google Scholar
Braudt, D. B. (2018). Sociogenomics in the 21st century: An introduction to the history and potential of genetically informed social science. Sociology Compass, 12(10), e12626.Google Scholar
Bublitz, J. C. (2013). My mind is mine!? Cognitive liberty as a legal concept. In Hildt, E. & Franke, A. G. (Eds.), Cognitive enhancement: An interdisciplinary perspective (pp. 233–264), Dordrecht: Springer.Google Scholar
Canli, T. (2007). The emergence of genomic psychology. EMBO Reports, 8(Special Issue), 530–534. www.ncbi.nlm.nih.gov/pmc/articles/PMC3327528/pdf/7400938.pdfCrossRefGoogle ScholarPubMed
Deciphering Developmental Disorders Study. (2017). Prevalence and architecture of de novo mutations in developmental disorders. Nature, 542(7642), 433–438. doi:10.1038/nature21062Google Scholar
Donnelly, J. (1989). Universal human rights in theory and practice. Ithaca, NY: Cornell University Press.Google Scholar
Harmon, S. (2005). The significance of UNESCO’s Universal Declaration on the Human Genome and Human Rights. SCRIPTed, 2(1), 18–47 www.research.ed.ac.uk/portal/files/18457597/Harmon_Significance_of_UNESCOs_Universal_Declaration_on_the_Human_Genome_and_Human_Rights.pdfGoogle Scholar
Khera, A. V., Chaffin, M., Aragam, K. G., Haas, M. E., Roselli, C., Choi, S. H., … Kathiresan, S. (2018). Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. Nature Genetics, 50(9), 1219–1224. doi:10.1038/s41588-018-0183-zGoogle Scholar
Kong, A., Thorleifsson, G., Frigge, M. L., Vilhjalmsson, B. J., Young, A. I., Thorgeirsson, T. E., … Gudbjartsson, D. F. (2018). The nature of nurture: Effects of parental genotypes. Science, 359(6374), 424–428. doi:10.1126/science.aan6877Google Scholar
Lee, J. J., Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., … Fontana, M. A. (2018). Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nature Genetics, 50(8), 1112–1121. doi:10.1038/s41588-018-0147-3Google Scholar
Liu, L., Sabo, A., Neale, B. M., Nagaswamy, U., Stevens, C., Lim, E., … Coon, H. (2013). Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls. PLOS Genetics, 9(4), e1003443. doi:10.1371/journal.pgen.1003443Google Scholar
Lodato, M. A., Rodin, R. E., Bohrson, C. L., Coulter, M. E., Barton, A. R., Kwon, M., … Yang, P. (2018) Aging and neurodegeneration are associated with increased mutations in single human neurons. Science, 359(6375), 555–559. doi:10.1126/science.aao4426CrossRefGoogle ScholarPubMed
Ienca, M., & Andorno, R. (2017), Towards new human rights in the age of neurotechnology. Life Sciences, Society and Policy, 13(5), 1–27. https://lsspjournal.biomedcentral.com/track/pdf/10.1186/s40504-017-0050-1CrossRefGoogle ScholarPubMed
Martin, A. R., Daly, M. J., Robinson, E. B., Hyman, S. E., & Neale, B. M. (2018). Predicting polygenic risk of psychiatric disorders. Biological Psychiatry. doi:10.1016/j.biopsych.2018.12.015Google Scholar
Martin, A. R., Gignoux, C. R., Walters, R. K., Wojcik, G. L., Neale, B. M., Gravel, S., … Kenny, E. E. (2017). Human demographic history impacts genetic risk prediction across diverse populations. American Journal of Human Genetics, 100(4), 635–649. doi:10.1016/j.ajhg.2017.03.004Google Scholar
Petrovski, S., & Goldstein, D. B. (2016). Unequal representation of genetic variation across ancestry groups creates healthcare inequality in the application of precision medicine. Genome Biology, 17(1), 157. doi:10.1186/s13059-016-1016-yGoogle Scholar
Qi, Q., Chu, A. Y., Kang, J. H., Jensen, M. K., Curhan, G. C., Pasquale, L. R., … Chasman, D. I. (2012). Sugar-sweetened beverages and genetic risk of obesity. New England Journal of Medicine, 367(15), 1387–1396.Google Scholar
Reference. (2019). What is the scope of psychology? www.reference.com/world-view/scope-psychology-41547aa6c8cc302cGoogle Scholar
Rende, R., & Slomkowski, C. (2009). Incorporating the family as a critical context in genetic studies of children: Implications for understanding pathways to risky behavior and substance use. Journal of Pediatric Psychology, 34(6), 606–616. www.ncbi.nlm.nih.gov/pubmed/18556676Google Scholar
Robinson, M. R., Hemani, G., Medina-Gomez, C., Mezzavilla, M., Esko, T., Shakhbazov, K., … Justice, A. E. (2015). Population genetic differentiation of height and body mass index across Europe. Nature Genetics, 47(11), 1357–1362. doi:10.1038/ng.3401Google Scholar
Sanders, S. J., Neale, B. M., Huang, H., Werling, D. M., An, J. Y., Dong, S., … Daly, M. J. (2017). Whole genome sequencing in psychiatric disorders: The WGSPD consortium. Nature Neuroscience, 20(12), 1661–1668. doi:10.1038/s41593-017-0017-9Google Scholar
Schüpbach, M., Gargiulo, M., Welter, M. L., Mallet, L., Béhar, C., Houeto, J. L., … Agid, Y. (2006). Neurosurgery in Parkinson disease: A distressed mind in a repaired body? Neurology, 66(12), 1811–1816.CrossRefGoogle Scholar
Visscher, P. M., Brown, M. A., McCarthy, M. I., & Yang, J. (2012). Five years of GWAS discovery. American Journal of Human Genetics, 90(1), 7–24. doi:10.1016/j.ajhg.2011.11.029Google Scholar
Visscher, P. M., Wray, N. R., Zhang, Q., Sklar, P., McCarthy, M. I., Brown, M. A., & Yang, J. (2017). 10 years of GWAS discovery: Biology, function, and translation. American Journal of Human Genetics, 101(1), 5–22. doi:10.1016/j.ajhg.2017.06.005CrossRefGoogle ScholarPubMed

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