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Chapter 9 - Antineuropathic Medications

from Part II - Common Categories of Pharmacologic Medications to Treat Chronic Pain

Published online by Cambridge University Press:  01 December 2023

By
Juyeon Kakazu  and
Alan D. Kaye
Edited by
Omar Viswanath  and
Ivan Urits
Omar Viswanath
Affiliation:
Creighton University, Omaha
Ivan Urits
Affiliation:
Southcoast Brain & Spine Center, Wareham
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Summary

Neuropathic pain (NP) is a subtype of chronic pain syndrome defined by International Association of the Study of Pain (IASP) as a “pain caused by a lesion or disease of the somatosensory system.” Consequence of CNS or PNS lesions are activities generated in the somatosensory system without peripheral afferent stimulation. The pathophysiology of the somatosensory system is injury causing complex ectopic signaling between neuronal pathways. There are several types of antineuropathic medications that are currently utilized to treat this subtype of pain, including gabapentin, pregabalin, and duloxetine, amongst others.

Keywords

antineuropathicnerve painantidepressantsantiepilepticsgabapentinpregabalin
Type
Chapter
Information
Cambridge Handbook of Pain Medicine , pp. 61 - 65
Publisher: Cambridge University Press
Print publication year: 2023

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References

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