Dynamic Epigenetic Impact of the Environment on the Developing Brain

doi:10.1017/9781108351959.003

3 - Dynamic Epigenetic Impact of the Environment on the Developing Brain

from Part I - Foundations

Published online by Cambridge University Press: 26 September 2020

Frances A. Champagne

Edited by

Jeffrey J. Lockman and

Catherine S. Tamis-LeMonda

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Jeffrey J. Lockman: Affiliation:
Tulane University, Louisiana
Catherine S. Tamis-LeMonda: Affiliation:
New York University

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Summary

Development is a dynamic process shaped by the interactions between genes and environments. Within the field of developmental biology, the complex interactions between genes and their products that create the foundation for cellular differentiation and the formation of the nervous system have been well described. Advances in molecular biology have permitted increasing precision in the characterization of the cascade of molecular changes that link genes to specific developmental endpoints. However, beyond addressing questions regarding the processes linking a gene to a phenotypic outcome, description of these molecular changes has also provided insight into the ways in which the environment induces lasting biological effects. Though environments – particularly characteristics of the social world around us – are typically viewed as a separate and distinct influence from genes, there is increasing understanding of the interplay between genes and environments.

Keywords

Epigenetics gene-environment interactions DNA methylation brain development maternal stress

Type: Chapter
Information: The Cambridge Handbook of Infant Development
Brain, Behavior, and Cultural Context
, pp. 70 - 93

DOI: https://doi.org/10.1017/9781108351959.003 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2020

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3 - Dynamic Epigenetic Impact of the Environment on the Developing Brain

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