This chapter explores how anime fan audiences have evolved since the 1950s regarding the development of physical venues and digital platforms. Fan audiences as “produser” (Bruns, 2008) consume, produce, and use anime and its related content through their various activities such as producing derivative works (dojinshi fanzines, music videos, and even games), performing cosplay, engaging in contents tourism, and so on. Fans’ deep commitment was incited by anime booms that happened in the 1960s, 1970s, and 1980s. The 1970s saw the beginning of the Comic Market, where fans can communicate with one another by selling and purchasing fanzines and performing cosplay, although the issue of copyright infringement has remained unsolved. Moreover, since the late 1990s, the internet and social media have facilitated the dissemination of anime and other contents produced through media mix (i.e., multimedia franchises) on an international scope. They also serve as platforms for fans to interact with each other domestically and globally.