Chapter One makes the case for a new way of seeing. Leaning on bell hooks and Rosemarie Garland-Thomson’s advocacy for an activist type of looking, it sets up some ways we might begin to read against – rather than with – the dominant narratives about disability. This chapter makes the first in a series of connections between classicism and coloniality that will recur in this book, and sees the process of reading bodies for meaning as rooted in colonial eugenics as well as classically-inspired physiognomy. Crucially for the argument of the book, the chapter concludes that reading bodies for meaning is neither a wholly classical nor a wholly colonial practice – and results instead from a particular way of looking back (or a linear inheritance model of classical reception). In closing, it introduces Michael Rothberg’s concept of the ‘implicated spectator’ as a way to return agency to the spectator in an assemblage-thinking model.