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9 - Bioinspired Design of Nanostructures

Inspiration from Viruses for Disease Detection and Treatment

from Part II - Structures

Published online by Cambridge University Press:  28 August 2020

By
Nicolas Anuku ,
John David Obayemi ,
Olushola S. Odusanya ,
Karen A. Malatesta  and
Wole Soboyejo
Edited by
Wole Soboyejo  and
Leo Daniel
Wole Soboyejo
Affiliation:
Worcester Polytechnic Institute, Massachusetts
Leo Daniel
Affiliation:
Kwara State University, Nigeria
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Summary

A growing number of developments in biology and materials chemistry highlight the notion of bioinspiration – in which biological concepts, mechanisms, functions, and design are the starting points toward new synthetic materials and devices with advanced structures and functions [1]. There is no doubt that emerging and reemerging infectious diseases caused and transmitted by viruses have significantly impacted human health worldwide [2,3]. Clearly, the virus exhibits elegant architectures that could occasionally be cellular macromolecules with structures that are beautifully adapted to the functions of the virion [4]. Virus particles exist in many sizes and shapes, and they vary considerably in the number and nature of the molecules from which they are built. Most viruses show a characteristic size, in the range of tens to hundreds of nanometers [5]. Viruses are intracellular parasites that enter a host cell/body to deliver their genetic material to initiate infection. Usually, the first step in the life cycle of a virus is the attachment to host cells/bodies. These may include their abilities to interact with lipids, proteins, and sugar moieties on the surface of cells and tissue [6].

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Bioinspired Structures and Design , pp. 212 - 232
Publisher: Cambridge University Press
Print publication year: 2020

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