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Chapter 81 - Thyroid, Parathyroid and Adrenal

from Section 9 - Endocrine Physiology

Published online by Cambridge University Press:  31 July 2019

David Chambers ,
Christopher Huang  and
Gareth Matthews
David Chambers
Affiliation:
Salford Royal NHS Foundation Trust
Christopher Huang
Affiliation:
University of Cambridge
Gareth Matthews
Affiliation:
University of Cambridge
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Summary

Triiodothyronine (T3), the strongly biologically active thyroid hormone. T3 comprises only 10% of the hormones released by the thyroid gland. In the circulation, T3 is very highly protein bound (99.7%), mainly to albumin, and has a short half-life (24 h). Only the unbound fraction of T3 is able to diffuse into the tissues to exert its effects.

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Basic Physiology for Anaesthetists , pp. 396 - 404
Publisher: Cambridge University Press
Print publication year: 2019

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References

Further reading

Molina, P. E.. Endocrine Physiology, 5th edition. New York, McGraw-Hill, 2018.Google Scholar
Kerr, D. E., Wenham, T., Newell-Price, J.. Endocrine problems in the critically ill 2: endocrine emergencies. BJA Education 2017; 17(11): 377–82.CrossRefGoogle Scholar
Miller, T., Gibbison, B., Russell, G. M.. Hypothalamic–pituitary–adrenal function during health, major surgery, and critical illness. BJA Education 2017; 17(1): 16–21.CrossRefGoogle Scholar
Ross, D. S.. Radioiodine therapy for hyperthyroidism. N Engl J Med 2011; 364(6): 542–50.CrossRefGoogle ScholarPubMed
Malhotra, S., Sodhi, V.. Anaesthesia for thyroid and parathyroid surgery. Continuing Educ Anaesth Crit Care Pain 2007; 7(2): 55–8.CrossRefGoogle Scholar

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