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Chapter 79 - Stress Response

from Section 8 - Energy Balance

Published online by Cambridge University Press:  31 July 2019

David Chambers
Affiliation:
Salford Royal NHS Foundation Trust
Christopher Huang
Affiliation:
University of Cambridge
Gareth Matthews
Affiliation:
University of Cambridge
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Summary

The stress response is a complex neuroendocrine response to physiological stress. The most commonly encountered stressors are trauma, burns, surgery and critical illness; the magnitude of the neuroendocrine response is directly related to the magnitude of the stressor. In addition to its metabolic effects, the stress response leads to activation of the immunological and haematological systems.

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Publisher: Cambridge University Press
Print publication year: 2019

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References

Further reading

Fant, F., Tina, E., Sandblom, D., et al. Thoracic epidural analgesia inhibits the neuro-hormonal but not the acute inflammatory stress response after radical retropubic prostatectomy. Br J Anaesth 2013; 110(5): 747–57.Google Scholar
Mikura, M., Yamaoka, I., Doi, M., et al. Glucose infusion suppresses surgery-induced muscle protein breakdown by inhibiting ubiquitin–proteasome pathway in rats. Anaesthesiology 2009; 110(1): 81–8.Google Scholar
Burton, D., Nicholson, G., Flail, G.. Endocrine and metabolic response to surgery. Continuing Educ Anaesth Crit Care Pain 2004; 4(5): 144–7.CrossRefGoogle Scholar
Desborough, J. P.. The stress response to trauma and surgery. Br J Anaesth 2000; 85(1): 109–17.CrossRefGoogle ScholarPubMed

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