Book contents
- Atlas of Pediatric Hematopathology
- Atlas of Pediatric Hematopathology
- Copyright page
- Contents
- Contributors
- Section I Peripheral Blood
- Section II Normal and Non-neoplastic Hematolymphoid Diseases
- Section III Mature Lymphoid Neoplasm
- Section IV Precursor Hematopoietic Neoplasms and Related Neoplasms
- Chapter 13 Precursor Lymphoblastic Leukemia/Lymphoma
- Chapter 14 Blastic Plasmacytoid Dendritic Cell Neoplasm
- Chapter 15 Acute Myeloid Leukemia and Related Precursor Neoplasms
- Chapter 16 Myeloproliferative Neoplasms
- Chapter 17 Myelodysplastic/Myeloproliferative Neoplasms
- Chapter 18 Childhood Myelodysplastic Syndrome
- Chapter 19 Germline Predisposition to Myeloid Neoplasia
- Chapter 20 Germline Predisposition to Lymphoid Neoplasm
- Chapter 21 Mastocytosis and Myeloid Lymphoid Neoplasms with Eosinophilia
- Section V Histiocytic Neoplasm and Miscellaneous Bone Marrow Diseases
- Index
- References
Chapter 16 - Myeloproliferative Neoplasms
from Section IV - Precursor Hematopoietic Neoplasms and Related Neoplasms
Published online by Cambridge University Press: 25 November 2023
- Atlas of Pediatric Hematopathology
- Atlas of Pediatric Hematopathology
- Copyright page
- Contents
- Contributors
- Section I Peripheral Blood
- Section II Normal and Non-neoplastic Hematolymphoid Diseases
- Section III Mature Lymphoid Neoplasm
- Section IV Precursor Hematopoietic Neoplasms and Related Neoplasms
- Chapter 13 Precursor Lymphoblastic Leukemia/Lymphoma
- Chapter 14 Blastic Plasmacytoid Dendritic Cell Neoplasm
- Chapter 15 Acute Myeloid Leukemia and Related Precursor Neoplasms
- Chapter 16 Myeloproliferative Neoplasms
- Chapter 17 Myelodysplastic/Myeloproliferative Neoplasms
- Chapter 18 Childhood Myelodysplastic Syndrome
- Chapter 19 Germline Predisposition to Myeloid Neoplasia
- Chapter 20 Germline Predisposition to Lymphoid Neoplasm
- Chapter 21 Mastocytosis and Myeloid Lymphoid Neoplasms with Eosinophilia
- Section V Histiocytic Neoplasm and Miscellaneous Bone Marrow Diseases
- Index
- References
Summary
Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by a proliferation of one or more of the myeloid lineages [1]. These components include erythroid cells, megakaryocytes, and granulocytes, the latter of which include eosinophils. In many cases, these MPNs are associated with acquired clonal genetic abnormalities involving cytoplasmic or receptor protein tyrosine kinases.
- Type
- Chapter
- Information
- Atlas of Pediatric Hematopathology , pp. 176 - 185Publisher: Cambridge University PressPrint publication year: 2023