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Chapter 7 - Infectious Diseases

from Section II - Normal and Non-neoplastic Hematolymphoid Diseases

Published online by Cambridge University Press:  25 November 2023

By
Shunyou Gong ,
Dehua Wang  and
Kristian T. Schafernak
Edited by
Silvia Tse Bunting ,
Xiayuan Liang ,
Michele E. Paessler  and
Satheesh Chonat
Silvia Tse Bunting
Affiliation:
Cleveland Clinic Florida Weston
Xiayuan Liang
Affiliation:
University of Colorado
Michele E. Paessler
Affiliation:
University of Pennsylvania School of Medicine
Satheesh Chonat
Affiliation:
Emory University, Atlanta
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Summary

Lymphadenopathy (LAD) refers to the enlargement and/or abnormal consistency of lymph nodes and may be localized or diffuse. It reflects the results of immune responses to different insulants such as infection, autoimmunity, or malignancy [1]. Children with LAD are much more likely to have benign etiologies than adults, and most commonly present with a cervical mass [2]. While most benign LADs in children have no identifiable cause and are defined as nonspecific reactive LAD, some cases are found to be of infectious origin, including bacteria, yeast, parasite, or virus, often referred to as lymphadenitis [3].

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Chapter
Information
Atlas of Pediatric Hematopathology , pp. 52 - 64
Publisher: Cambridge University Press
Print publication year: 2023

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References

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