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from Part II - Flies
Published online by Cambridge University Press: 26 February 2021
We start with an odd mutation in flies that causes their legs to be double-jointed, but what is even stranger is that the extra joints are upside-down. This leads to a discussion of cell polarity not only in flies but also in the inner ear of humans. Two intercellular signaling pathways are involved:PCP and Notch.
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