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Chapter 12 - Autoimmune Hemolytic Anemia

from Section 3, Part D - Hemolytic Anemias

Published online by Cambridge University Press:  18 April 2018

By
Mark A. Murakami ,
Edward J. Benz  and
Nancy Berliner
Edited by
Edward J. Benz, Jr. ,
Nancy Berliner  and
Fred J. Schiffman
Edward J. Benz, Jr.
Affiliation:
Dana Farber Cancer Institute
Nancy Berliner
Affiliation:
Brigham and Women's Hospital, Boston
Fred J. Schiffman
Affiliation:
Children's Hospital, Boston
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Type
Chapter
Information
Anemia
Pathophysiology, Diagnosis, and Management
 , pp. 84 - 94
Publisher: Cambridge University Press
Print publication year: 2017

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References

Sokol, RJ, Booker, DJ, Stamps, R. The pathology of autoimmune haemolytic anaemia. J Clin Pathol. 1992; 45(12): 1047–1052.Google Scholar
Sachs, UJ, et al. Does a negative direct antiglobulin test exclude warm autoimmune haemolytic anaemia? A prospective study of 504 cases. Br J Haematol. 2006; 132(5): 655–656.CrossRefGoogle ScholarPubMed
Wheeler, CA, Calhoun, L, Blackall, DP. Warm reactive autoantibodies: clinical and serologic correlations. Am J Clin Pathol. 2004; 122(5): 680–685.CrossRefGoogle ScholarPubMed
Vos, GH, Petz, L, Fudenberg, HH. Specificity of acquired haemolytic anaemia autoantibodies and their serological characteristics. Br J Haematol. 1970; 19(1): 57–66.CrossRefGoogle ScholarPubMed
Garratty, G, Arndt, PA. An update on drug-induced immune hemolytic anemia. Immunohematology. 2007; 23(3): 105–119.CrossRefGoogle ScholarPubMed
Worlledge, SM, Carstairs, KC, Dacie, JV. Autoimmune haemolytic anaemia associated with alpha-methyldopa therapy. Lancet. 1966; 2(7455): 135–139.CrossRefGoogle ScholarPubMed
Garratty, G, Petz, LD. Drug-induced immune hemolytic anemia. Am J Med. 1975; 58(3): 398–407.CrossRefGoogle ScholarPubMed
Mueller-Eckhardt, C, Salama, A. Drug-induced immune cytopenias: a unifying pathogenetic concept with special emphasis on the role of drug metabolites. Transfus Med Rev. 1990;4(1): 69–77.CrossRefGoogle ScholarPubMed
Garratty, G, Arndt, PA. Positive direct antiglobulin tests and haemolytic anaemia following therapy with beta-lactamase inhibitor containing drugs may be associated with nonimmunologic adsorption of protein onto red blood cells. Br J Haematol. 1998; 100(4): 777–783.Google Scholar
Leger, RM, Garratty, G. Evaluation of methods for detecting alloantibodies underlying warm autoantibodies. Transfusion. 1999;39(1): 11–16.CrossRefGoogle ScholarPubMed
Lechner, K, Jäger, U. How I treat autoimmune hemolytic anemias in adults. Blood. 2010; 116(11): 1831–1838.CrossRefGoogle Scholar
Murphy, S, LoBuglio, AF. Drug therapy of autoimmune hemolytic anemia. Semin Hematol. 1976; 13(4): 323–334.Google ScholarPubMed
Gehrs, BC, Friedberg, RC. Autoimmune hemolytic anemia. Am J Hematol. 2002; 69(4): 258–271.Google Scholar
Akpek, G, McAneny, D, Weintraub, L. Comparative response to splenectomy in Coombs-positive autoimmune hemolytic anemia with or without associated disease. Am J Hematol. 1999; 61(2): 98–102.Google Scholar
Atkinson, JP, Schreiber, AD, Frank, MM. Effects of corticosteroids and splenectomy on the immune clearance and destruction of erythrocytes. J Clin Invest. 1973; 52(6): 1509–1517.CrossRefGoogle ScholarPubMed
Casaccia, M, et al. Laparoscopic splenectomy for hematologic diseases: a preliminary analysis performed on the Italian Registry of Laparoscopic Surgery of the Spleen (IRLSS). Surg Endosc. 2006; 20(8): 1214–1220.CrossRefGoogle ScholarPubMed
Ikeda, M, et al. High incidence of thrombosis of the portal venous system after laparoscopic splenectomy: a prospective study with contrast-enhanced CT scan. Ann Surg. 2005; 241(2): 208–216.CrossRefGoogle ScholarPubMed
Advisory Committee on Immunization Practices (ACIP) recommended immunization schedules for persons aged 0 through 18 years and adults aged 19 years and older–United States, 2013. MMWR Surveill Summ. 2013(62 Suppl 1): 1.Google Scholar
D’Arena, G, et al. Rituximab therapy for chronic lymphocytic leukemia-associated autoimmune hemolytic anemia. Am J Hematol. 2006; 81(8): 598–602.Google Scholar
Bussone, G, et al. Efficacy and safety of rituximab in adults’ warm antibody autoimmune haemolytic anemia: retrospective analysis of 27 cases. Am J Hematol. 2009; 84(3): 153–157.Google Scholar
Dierickx, D, et al. Rituximab in auto-immune haemolytic anaemia and immune thrombocytopenic purpura: a Belgian retrospective multicentric study. J Intern Med. 2009; 266(5):484–491.Google Scholar
Narat, S, et al. Rituximab in the treatment of refractory autoimmune cytopenias in adults. Haematologica. 2005; 90(9):1273–1274.Google ScholarPubMed
Anderson, D, et al. Guidelines on the use of intravenous immune globulin for hematologic conditions. Transfus Med Rev. 2007; 21(2 Suppl 1):S9–56.CrossRefGoogle ScholarPubMed
Gertz, MA. Cold agglutinin disease and cryoglobulinemia. Clin Lymphoma. 2005; 5(4):290–293.CrossRefGoogle ScholarPubMed
Bessman, JD, Banks, D. Spurious macrocytosis, a common clue to erythrocyte cold agglutinins. Am J Clin Pathol. 1980; 74(6):797–800.CrossRefGoogle ScholarPubMed
Rosse, WF, Adams, JP. The variability of hemolysis in the cold agglutinin syndrome. Blood. 1980; 56(3):409–16.CrossRefGoogle ScholarPubMed
Feizi, T. Monotypic cold agglutinins in infection by mycoplasma pneumoniae. Nature. 1967; 215(5100):540–542.CrossRefGoogle ScholarPubMed
Horwitz, CA, et al. Cold agglutinins in infectious mononucleosis and heterophil-antibody-negative mononucleosis-like syndromes. Blood. 1977; 50(2):195–202.CrossRefGoogle ScholarPubMed
Swiecicki, PL, Hegerova, LT, Gertz, MA. Cold agglutinin disease. Blood. 2013; 122(7):1114–1121.CrossRefGoogle ScholarPubMed
Nydegger, UE, Kazatchkine, MD, Miescher, PA. Immunopathologic and clinical features of hemolytic anemia due to cold agglutinins. Semin Hematol. 1991; 28(1):66–77.Google ScholarPubMed
Jaffe, CJ, Atkinson, JP, Frank, MM. The role of complement in the clearance of cold agglutinin-sensitized erythrocytes in man. J Clin Invest. 1976; 58(4):942–949.CrossRefGoogle ScholarPubMed
Mickley, H, Sorensen, PG. Immune haemolytic anaemia associated with ampicillin dependent warm antibodies and high titre cold agglutinins in a patient with Mycoplasma pneumonia. Scand J Haematol. 1984; 32(3):323–326.Google Scholar
Ulvestad, E. Paradoxical haemolysis in a patient with cold agglutinin disease. Eur J Haematol. 1998; 60(2):93–100.CrossRefGoogle Scholar
Berentsen, S, et al. High response rate and durable remissions following fludarabine and rituximab combination therapy for chronic cold agglutinin disease. Blood. 2010; 116(17):3180–3184.CrossRefGoogle ScholarPubMed
Berentsen, S, et al. Rituximab for primary chronic cold agglutinin disease: a prospective study of 37 courses of therapy in 27 patients. Blood. 2004; 103(8):2925–2928.CrossRefGoogle ScholarPubMed
Berentsen, S, et al. Primary chronic cold agglutinin disease: a population based clinical study of 86 patients. Haematologica. 2006; 91(4):460–466.Google ScholarPubMed
Schollkopf, C, et al. Rituximab in chronic cold agglutinin disease: a prospective study of 20 patients. Leuk Lymphoma. 2006; 47(2):253–260.CrossRefGoogle ScholarPubMed
Ghielmini, M, et al. Effect of single-agent rituximab given at the standard schedule or as prolonged treatment in patients with mantle cell lymphoma: a study of the Swiss Group for Clinical Cancer Research (SAKK). J Clin Oncol. 2005; 23(4):705–711.CrossRefGoogle ScholarPubMed
Hoppe, B, et al. Response to intravenous immunoglobulin G in an infant with immunoglobulin A-associated autoimmune haemolytic anaemia. Vox Sang. 2004; 86(2):151–153.CrossRefGoogle Scholar
Geurs, F, et al. Successful plasmapheresis in corticosteroid-resistant hemolysis in infectious mononucleosis: role of autoantibodies against triosephosphate isomerase. Acta Haematol. 1992; 88(2–3):142–146.Google Scholar
Berentsen, S. How I manage cold agglutinin disease. Br J Haematol. 2011; 153(3):309–317.CrossRefGoogle Scholar
Heddle, NM. Acute paroxysmal cold hemoglobinuria. Transfus Med Rev. 1989; 3(3):219–229.CrossRefGoogle ScholarPubMed
Sivakumaran, M, et al. Paroxysmal cold haemoglobinuria caused by non-Hodgkin’s lymphoma. Br J Haematol. 1999; 105(1):278–279.Google Scholar
Ries, CA, et al. Paroxysmal cold hemoglobinuria: report of a case with an exceptionally high thermal range Donath-Landsteiner antibody. Blood. 1971; 38(4):491–499.Google Scholar
Rausen, AR, et al. Compatible transfusion therapy for paroxysmal cold hemoglobinuria. Pediatrics. 1975; 55(2):275–278.Google Scholar
Koppel, A, et al. Rituximab as successful therapy in a patient with refractory paroxysmal cold hemoglobinuria. Transfusion. 2007; 47(10):1902–1904.Google Scholar
Gregory, GP, et al. Failure of eculizumab to correct paroxysmal cold hemoglobinuria. Ann Hematol. 2011; 90(8):989–990.CrossRefGoogle ScholarPubMed
Schrier, SL. Clinical Features and Diagnosis of Autoimmune Hemolytic Anemia: Warm Agglutinins. UpToDate; 2013. Retrieved April 7, 2014, from www.uptodate.com/contents/clinical-features-and-diagnosis-of-autoimmune-hemolytic-anemia-warm-agglutinins?source=search_result&search=autoimmune+hemolytic+anemia&selectedTitle=1~128.Google Scholar
Lichtman, MA, Williams, WJ. Williams hematology. 7th ed. New York: McGraw-Hill, Medical Pub. Division; 2006.Google Scholar
Kauke, T, Reininger, AJ. Images in clinical medicine. Livedo reticularis and cold agglutinins. N Engl J Med. 2007; 356(3):284.Google Scholar

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