In Gregory of Nyssa’s dialogue, On Soul and Resurrection, Macrina addresses questions about the nature of the soul and the possibility of survival after death. Her conversation involves striking similarities to Socrates’ arguments in Plato’s Phaedo. Both Macrina and Socrates are about to die, and both discourse about the soul and immortality. However, while Socrates’ arguments are commonly taught in classrooms around the world, Macrina’s arguments are widely neglected. This chapter argues that we should correct this oversight and pay more attention to Macrina as we include women in the philosophical canon of antiquity. Although no extant texts authored by her have survived, the chapter shows how the external evidence left by Gregory suggests Macrina is a worthy philosopher in her own right. She was not silent during her life. We should not allow her to remain silent in death.