This chapter summarizes lessons learned across the exemplary models presented in this book, providing a path forward in furthering prevention science and in charting a course for future directions in the specialty of prevention. A blueprint is offered for training, interdisciplinary community collaborations, program evaluation, and dissemination of evidence. Concrete steps that are necessary to foster a prevention mindset in the field of mental health are outlined. The first step is generating the “will” to reorient our psychological practice, policies, and research to a prevention focus. A second step is to position the training environment to be supportive of and to value prevention, health promotion, and social justice. A third step is to orient our healthcare systems and funding resources to include support for and to engage in prevention work. It is clear that prevention has utility in the current mental health landscape. A genuine prevention outlook is necessary to move from a reactionary approach based on illness to a proactive approach rooted in fostering strengths and wellness and aimed at averting and reducing human suffering. Ultimately, readers are invited to be leaders in translating the vision presented in this book into intentional prevention practice, research, and training.