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14 - Abdominal aortic aneurysm

Published online by Cambridge University Press:  07 September 2009

Janet T. Powell
Affiliation:
Department of Vascular Surgery, Imperial College School of Medicine, London
Beverley J. Hunt
Affiliation:
University of London
Lucilla Poston
Affiliation:
University of London
Michael Schachter
Affiliation:
Imperial College of Science, Technology and Medicine, London
Alison W. Halliday
Affiliation:
St George's Hospital, London
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Summary

Introduction

The aorta has to withstand the load imposed by arterial blood pressure for a lifetime. The microanatomy of the aorta reflects this burden and the media is thick, composed of numerous concentric lamellae of elastic connective tissue and smooth muscle cells. In youth and health elastin is the principal load-bearing component of the aorta with collagen fibres only being recruited at the highest loads (Burton, 1954). Other microfibrils, including fibrillin-rich fibrils, also contribute to load bearing. The abdominal aorta, distal to the renal arteries, is the aortic segment with least elastin and least nutrient vasa vasorum in the adventitia. With ageing this segment of the aorta is vulnerable to weakening and fusiform aneurysmal dilatation: abdominal aortic aneurysms (AAAs) are present in approximately 5% of men aged 65 years or older.

Definition of an abdominal aortic aneurysm

The normal diameter of the infrarenal aorta is 1.5–2.2 cm, with taller patients tending to have wider aortas. The infrarenal aorta is conveniently assessed by ultrasonography. A localized fusiform dilation is clearly evidenced when the proximal and distal aortic diameters are much smaller than the maximum diameter. One suggested definition of an AAA is when the ratio of maximum diameter to infrarenal diameter exceeds 1.5 cm. However, the resolution and visualization of the suprarenal aorta by ultrasonography are poor. A more convenient and widely accepted definition of an aneurysm is when the maximum anterior–posterior diameter exceeds 3 cm.

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An Introduction to Vascular Biology
From Basic Science to Clinical Practice
, pp. 318 - 326
Publisher: Cambridge University Press
Print publication year: 2002

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