In this chapter, we look at Mesoamerican views on human activity and life. How did precolonial Mesoamerican philosophers think about proper or right action, in the case of the individual and the wider community? This includes issues such as the role of the state, the ruler, and the individual’s duties toward each. The chapter focuses on key ethical concepts and views in Mesoamerican traditions, such as those concerning humility, sacrifice, and the situational and temporary nature of goodness.