What brings speculative realism and posthumanism together is a mutual understanding that, while the non-human world might be unexpected or unknowable, it is nevertheless real. Strategies for confronting this reality are the focus of this chapter. Although there are different strands of speculative realism, all are based on the argument that while there is a divide between human and non-human worlds, this divide can be crossed, either directly or indirectly. Thus although we can never really know the other because it is outside of human experience, this does not mean there is an unbreachable gap, because art is created by the tension between humanity and the world-beyond-humanity, exceeding even the concepts of art’s creators. Work by Kazuo Ishiguro, Solmaz Sharif, Christian Bök, Denis Villeneuve, and Juliana Spahr is used to develop this thesis.