Intra-African cooperation is multifaceted. This chapter will show that with reference to bilateral contacts between states – or often between leaders – that are sometimes close and at others less so and with reference to intergovernmental organizations that are sometimes close and at others less so. At the continental level, those organizations include the Organization of African Unity and its successor organization, the African Union, as well as regional economic communities like the Economic Community of West African States or the Southern African Development Community. The chapter also investigates the drivers and obstacles for political and economic cooperation and integration and shows how leaders benefit from the status quo.