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Chapter 16 - The Role of the Placenta in DOHaD

from Section IV - Mechanisms

Published online by Cambridge University Press:  01 December 2022

By
Rohan M. Lewis  and
Amanda N. Sferruzzi-Perri
Edited by
Lucilla Poston ,
Keith M. Godfrey ,
Peter D. Gluckman  and
Mark A. Hanson
Lucilla Poston
Affiliation:
King's College London
Keith M. Godfrey
Affiliation:
University of Southampton
Peter D. Gluckman
Affiliation:
University of Auckland
Mark A. Hanson
Affiliation:
University of Southampton
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Summary

Placental function supports the growth and development of the fetus by providing nutrients, removing fetal waste and protecting the fetus from xenobiotics. The placenta also secretes hormones and other endocrine mediators that adapt maternal physiology to support the pregnancy. Where placental function is inadequate, fetal development may be compromised and result in persistent changes in organ structure and function that have consequences for later health.

Type
Chapter
Information
Developmental Origins of Health and Disease , pp. 166 - 175
Publisher: Cambridge University Press
Print publication year: 2022

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References

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