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10 - Imaging of treated bladder cancer

Published online by Cambridge University Press:  25 August 2009

David MacVicar
Affiliation:
Royal Marsden Hospital
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Summary

Imaging has a well-established role in the pre-treatment assessment of bladder cancer. Staging of muscle invasive tumors with CT or MRI is accurate and has an immediate effect on treatment decisions [1–3]. However, the role of imaging in monitoring the effects of treatment and in the follow-up of the treated patient is less well defined.

This chapter will consider the role of imaging in the diagnosis of treatment-related complications, the recognition of normal post-treatment tissue appearances and the assessment of treatment response as well as the role of imaging in patient follow-up and the diagnosis of local tumor recurrence.

Although a small number of patients have other pathologies, the vast majority of bladder cancers are transitional cell carcinomas (TCC), and this chapter will focus solely on this tumor type. The choice of treatment modality in bladder cancer is dependent on many factors; the most important are the stage and histological grade of the tumor, but other important factors include the patient's performance status and co-morbidities, patient preference and the preference and expertise of the treatment center. There are large geographical variations in treatment preferences; in particular, patients with muscle invasive tumors are more likely to be treated with radiotherapy in the UK, compared with the United States.

Imaging following surgery

Transurethral resection and biopsy

Over 80% of bladder cancer patients have superficial (non–muscle invasive) tumors. These patients are usually treated by transurethral resection of the bladder tumor (TURBT).

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Publisher: Cambridge University Press
Print publication year: 2008

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References

Husband, J E, Olliff, J F, Williams, M Pet al. Bladder cancer: staging with CT and MR imaging. Radiology 1989; 173: 435–40.CrossRefGoogle ScholarPubMed
Kim, B, Semelka, R C, Ascher, S Met al. Bladder tumour staging: comparison of contrast-enhanced CT, T1- and T2-weighted MR imaging, dynamic gadolinium-enhanced imaging and late gadolinium-enhanced imaging. Radiology 1994; 193: 239–45.CrossRefGoogle ScholarPubMed
Tanimoto, A, Yuasa, Y, Imai, Yet al. Bladder tumour staging: comparison of conventional and gadolinium-enhanced dynamic MR imaging and CT. Radiology 1992; 185: 741–7.CrossRefGoogle ScholarPubMed
Hautmann, R E, Stein, J P. Neobladder with prostatic capsule and seminal-sparing cystectomy for bladder cancer: a step in the wrong direction. Urol Clin North Am. 2005; 32: 177–85.CrossRefGoogle ScholarPubMed
Hahn, P F, Saini, S, Stark, D Det al. Intraabdominal hematoma: the concentric-ring sign in MR imaging. AJR Am J Roentgenol 1987; 148: 115–19.CrossRefGoogle ScholarPubMed
Naik, K S, Carrington, B M, Yates, W, Clarke, N W. The post-cystectomy pseudotumour sign: MRI appearances of a modified chronic pelvic haematoma due to retained haemostatic gauze. Clin Radiol 2000; 55: 970–4.CrossRefGoogle ScholarPubMed
Kokubo, T, Itai, Y, Ohtomo, Ket al. Retained surgical sponges: CT and US appearance. Radiology 1987; 165: 415–18.CrossRefGoogle ScholarPubMed
Kalovidouris, A, Kehagias, D, Moulopoulos, Let al. Abdominal retained surgical sponges: CT appearance. Eur Radiol 1999; 9: 1407–10.CrossRefGoogle ScholarPubMed
Sugimura, H, Tamura, S, Kakitsubata, Yet al. Magnetic resonance imaging of retained surgical sponges. Case report. Clin Imaging 1992; 16: 259–62.CrossRefGoogle ScholarPubMed
Heaney, M D, Francis, I R, Cohan, R Het al. Orthotopic neobladder reconstruction: findings on excretory urography and CT. AJR Am J Roentgenol 1999; 172: 1213–20.CrossRefGoogle ScholarPubMed
vanSonnenberg, E, Wittich, G R, Casola, Get al. Lymphoceles: imaging characteristics and percutaneous management. Radiology 1986; 161: 593–6.CrossRefGoogle ScholarPubMed
Nieder, A M, Sved, P D, Stein, J Pet al. Cystoprostatectomy and orthotopic ileal neobladder reconstruction for management of bacille Calmette Guerin-induced bladder contractures. Urology. 2005; 65: 909–12.CrossRefGoogle ScholarPubMed
Miller, A B, Hoogstraten, B, Staquet, M, Winkler, A. Reporting results of cancer treatment. Cancer 1981; 47: 207–14.3.0.CO;2-6>CrossRefGoogle ScholarPubMed
Therasse, P, Arbuck, S G, Eisenhauer, E Aet al. New guidelines to evaluate the response to treatment in solid tumours. J Natl Cancer Inst 2000; 92: 205–16.CrossRefGoogle Scholar
Schrier, B P, Peters, M, Barentsz, J O, Witjes, J A. Evaluation of chemotherapy with magnetic resonance imaging in patients with regionally metastatic or unresectable bladder cancer. Eur Urol 2006; 49: 698–703.CrossRefGoogle ScholarPubMed
Barentsz, J O, Berger-Hartog, O, Witjes, J Aet al. Evaluation of chemotherapy in advanced urinary bladder cancer with fast dynamic contrast-enhanced MR imaging. Radiology 1998; 207: 791–7.CrossRefGoogle ScholarPubMed
Johnson, R J, Carrington, B M. Pelvic radiation disease. Clin Radiol 1992; 45: 4–12.CrossRefGoogle ScholarPubMed
Sugimura, K, Carrington, B M, Quivey, J M, Hricak, H. Postirradiation changes in the pelvis: assessment with MR imaging. Radiology 1990; 175: 805–13.CrossRefGoogle ScholarPubMed
Worawattanakul, S, Semelka, R C, Kelekis, N L. Post radiation hemorrhagic cystitis: MR findings. Magn Reson Imaging 1997; 15: 1103–6.CrossRefGoogle ScholarPubMed
Blomlie, V, Rofstad, E K, Skjonsberg, Aet al. Female pelvic bone marrow: serial MR imaging before, during and after radiation therapy. Radiology 1995; 194: 537–43.CrossRefGoogle Scholar
Blomlie, V, Rofstad, E K, Talle, Ket al. Incidence of radiation-induced insufficiency fractures of the female pelvis: evaluation with MR imaging. AJR Am J Roentgenol 1996; 167: 1205–10.CrossRefGoogle ScholarPubMed
Kanberoglu, K, Mihmanli, I, Kurugoglu, Set al. Bone marrow changes adjacent to the sacroiliac joints after pelvic radiotherapy mimicking metastases on MRI. Eur Radiol 2001; 11: 1748–52.CrossRefGoogle ScholarPubMed
Wignall, T A, Carrington, B M, Logue, J P. Post-radiotherapy osteomyelitis of the symphysis pubis: computed tomographic features. Clin Radiol 1998; 53: 126–30.CrossRefGoogle ScholarPubMed
Mitchell, D G, Rao, V M, Dalinka, M Ket al. Femoral head avascular necrosis: correlation of MR imaging, radiographic staging, radionuclide imaging, and clinical findings. Radiology 1987; 162: 709–15.CrossRefGoogle ScholarPubMed
Barentsz, J O, Jager, G J, Vierzen, P Bet al. Staging urinary bladder cancer after transurethral biopsy: value of fast dynamic contrast-enhanced MR imaging. Radiology 1996; 201: 185–93.CrossRefGoogle ScholarPubMed
Dobson, M J, Carrington, B M, Collins, C Det al. The assessment of irradiated bladder carcinoma using dynamic contrast-enhanced MR imaging. Clin Radiol 2001; 56: 94–8.CrossRefGoogle ScholarPubMed
Bochner, B H, Montie, J E, Lee, C T. Follow-up strategies and management of recurrence in urologic oncology bladder cancer: Invasive bladder cancer. Urol Clin North Am; 2003; 30: 777–89.CrossRefGoogle ScholarPubMed
Malkowicz, S B, Poppel, H, Mickisch, Get al. Muscle-invasive urothelial carcinoma of the bladder. Urology 2007; 69(1 suppl): 3–16.CrossRefGoogle ScholarPubMed
Stein, J P, Lieskovsky, G, Cote, Ret al. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001; 19: 666–75.CrossRefGoogle ScholarPubMed
Koh, D M, Husband, J E. Patterns of recurrence of bladder carcinoma following radical cystectomy. Cancer Imaging 2003; 3: 96–100.Google Scholar
Hassan, J M, Cookson, M S, Smith, J A, Chang S S. Patterns of initial transitional cell recurrence in patients after cystectomy. J Urol 2006; 175: 2054–7.CrossRefGoogle ScholarPubMed
Hassan, J M, Cookson, M S, Smith, J A, Chang, S S. Urethral recurrence in patients following orthotopic urinary diversion. J Urol 2004; 172(4 Pt 1): 1338–41.CrossRefGoogle ScholarPubMed
Nieder, A M, Sved, P D, Gomez, Pet al. Urethral recurrence after cystoprostatectomy: implications for urinary diversion and monitoring. Urology 2004; 64: 950–4.CrossRefGoogle Scholar
Werf-Messing, B, Menon, R S, Hop, W C. Cancer of the urinary bladder category T2, T3 (NxM0) treated by interstitial radium implant: second report. Int J Radiat Oncol Biol Phys 1983; 9: 481–5.CrossRefGoogle Scholar
Kenworthy, P, Tanguay, S, Dinney, C P. The risk of upper tract recurrence following cystectomy in patients with transitional cell carcinoma involving the distal ureter. J Urol 1996; 155(February): 501–3.CrossRefGoogle ScholarPubMed
Cowan, R A, McBain, C A, Ryder, W Det al. Radiotherapy for muscle invasive carcinoma of the bladder: results of a randomized trial comparing conventional whole bladder with dose-escalated partial bladder radiotherapy. Int J Radiat Oncol Biol Phys 2004; 59: 197–207.CrossRefGoogle ScholarPubMed
Deserno, W M, Harisinghani, M G, Taupitz, Met al. Urinary bladder cancer: preoperative nodal staging with ferumoxtran-10-enhanced MR imaging. Radiology 2004; 233(2): 449–56.CrossRefGoogle ScholarPubMed
Picchio, M, Treiber, U, Beer, A Jet al. Value of 11C-choline PET and contrast-enhanced CT for staging of bladder cancer: correlation with histopathologic findings. J Nucl Med 2006; 47: 938–44.Google ScholarPubMed
Browne, R F, Meehan, C P, Colville, Jet al. Transitional cell carcinoma of the upper urinary tract: spectrum of imaging findings. Radiographics 2005; 25: 1609–27.CrossRefGoogle ScholarPubMed
Westney, O L, Pisters, L L, Pettaway, C Aet al. Presentation, methods of diagnosis and therapy for pelvic recurrence following radical cystectomy for transitional cell carcinoma of the bladder. J Urol 1998; 159: 792–5.CrossRefGoogle ScholarPubMed
Slaton, J W, Swanson, D A, Grossman, H B, Dinney, C P. A stage specific approach to tumour surveillance after radical cystectomy for transitional cell carcinoma of the bladder. J Urol 1999; 162: 710–14.CrossRefGoogle ScholarPubMed
Recommendations for Cross-Sectional Imaging in Cancer Management: Computed tomography – CT, Magnetic resonance imaging – MRI, Positron emission tomography – PET, Issue 2. The Royal College of Radiologists (2006), London, UK. RCR Ref No RCR (06)1.
,European Association of Urology. Guidelines, Arnhem, The Netherlands: European Association of Urology, 2006.Google Scholar

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