We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.
Yes
from Section III - Ovarian Cancer
Published online by Cambridge University Press: 20 July 2023
Age is an independent predictor of survival in advanced ovarian cancer. However, inadequate therapy appears to be a driver for decreased survival among elderly patients with cancer. Multiple randomized control trials have demonstrated equivalent oncologic outcomes with neoadjuvant chemotherapy compared to primary cytoreduction with reduced perioperative complications and mortality, decided by a gynecologic oncology surgeon. A national database study demonstrates an improvement in the receipt of both surgery and chemotherapy over time with high adoption of NACT contributing to an improvement in outcomes. In an elderly population, NACT results in a 70% reduction in perioperative mortality. All patients 75 years of age or older with one medical co-morbidity are the highest risk group for postoperative mortality (average 30-day post-operative mortality of 13% with primary surgery). These patients likely will benefit the most from NACT and should be considered routine practice for elderly patients with advanced ovarian cancer.
To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Find out more about the Kindle Personal Document Service.
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.
