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While cancer affects primarily the elderly, it also occurs in younger age groups, with different implications specifically relating to reproduction. Cancer can also occur during pregnancy itself. This brings together two diverse areas of medicine, encompassing the complexity of cancer and its varied biology and the equally challenging areas of fertility, conception and pregnancy. The 55th RCOG Study Group brought together a range of experts to examine these issues. This book presents the findings of the Study Group, with sections covering:epidemiology, genetics and basic principles of chemotherapy and radiotherapyfertility issues and paediatric cancersgynaecological cancers and precancerdiagnostic dilemmasthe placentanon-gynaecological cancersmultidisciplinary care and service provision.
The 54th RCOG Study Group brought together a range of experts from across many disciplines to examine the most up-to-date evidence on all aspects of diagnosis and management in women with renal problems before, during and after pregnancy. This book presents the findings of the Study Group, describing many of the issues likely to be faced in clinical practice and providing valuable information for all healthcare professionals working in this field. General principles for optimal management are clearly defined and separate chapters are devoted to specific disease entities and/or clinical situations. Many controversial areas - such as management of hypertension, diagnosis of pre-eclampsia, assisted conception, rationalisation of the many medications used in nephrology practice, renal biopsy, surgical emergencies, patient input and responsibilities - are carefully considered.
Polycystic ovary syndrome (PCOS) is the most common endocrine disturbance, affecting 10-15% of women in the UK. The definition of PCOS has been much debated, while its pathophysiology appears to be multifactorial and is still being actively researched. There is no doubt that PCOS has a significant effect on quality of life and psychological morbidity and, as many specialists are involved in its management, a multidisciplinary approach is required. The 59th RCOG Study Group brought together a range of experts who treat women with PCOS. This book presents the findings of the Study Group, including:A definition of PCOSThe accuracy of diagnostic interventionsThe particular challenges of adolescent diagnosis and managementThe correlation to ethnicityCurrent approaches to therapyThe potential individualisation of therapy The role of the alternative therapies used to manage some aspects of PCOS.
Successful implantation and early development need a union of healthy genes and an optimal uterine environment. The 48th RCOG Study Group, an international multidisciplinary expert forum, considered factors involved in preparation for implantation within the uterus; how to determine a good egg and good sperm; lessons from animal models; transgenic and genomic technologies; sporadic and recurrent early pregnancy loss; single-embryo transfer; and the developmental consequences of assisted reproduction technologies. This book presents the findings of the Study Group, with sections covering:preparation for implantation - the uterine environmentthe embryolessons from animal models (transgenics) and novel technologiesclinical sequelae.
Reproductive ageing affects both individuals and wider society, and obstetricians and gynaecologists are witness to the impact of reproductive ageing and to some of the fears and misapprehensions of the general public. This book raises awareness of societal trends and their implications. The wider importance of the subject to the whole of society is emphasized by contributions from outside the world of obstetrics and gynaecology, both within and outside medicine. The 56th RCOG Study Group brought together a range of experts to examine reproductive ageing. This book presents the findings of the Study Group, with sections covering:background to ageing and demographicsbasic science of reproductive ageingpregnancy: the ageing mother and medical needsthe outcomes: children and mothersfuture fertility insurance: screening, cryopreservation or egg donors?sex beyond and after fertilityfertility treatment: science and reality - the NHS and the marketthe future: dreams and waking up.
Great progress has been made in genetics in recent years, with significant consequences for the field of reproductive genetics. The ability to identify genetic defects before implantation, to diagnose fetal abnormalities and to introduce screening programmes means that genetic testing now has a major role in preventive medicine. The 57th RCOG Study Group brought together a range of experts to examine the many clinical, ethical and societal issues around reproductive genetics. This book presents the findings of the Study Group, covering a range of disorders, advances in treatments and techniques, as well as the importance of educating the public and the potential ethical dilemmas that may arise as a result of new scientific findings and new methodologies.
Gynaecological cancers are categorised as 'rare' diseases, although collectively they affect over 16,000 women each year in the UK alone. There is a lack of real understanding of these conditions compared with other malignancies, possibly owing to their relative rarity when viewed as individual diseases. The 60th RCOG Study Group brought together a range of experts to examine as many biological aspects of gynaecological cancers as possible, including both surgical and non-surgical therapies. This book presents the findings of the Study Group, with contents including:current understanding of the biology of gynaecological cancerstranslation of biology to the clinicstate of the art in imaging and therapycurrent clinical trialsadvances in multimodal therapyindividualised treatment.
Millennium Development Goals (MDGs) 4 and 5, created under the auspices of the United Nations, challenged political, financial, medical and civil society leaders to improve both child and maternal health. The 58th RCOG Study Group brought together a range of experts - including midwives, obstetricians and gynaecologists, anaesthetists and paediatricians - to provide an up-to-date review of progress to date and the challenges around meeting these MDGs. This book presents the findings of the Study Group, with sections covering:the size of the problemclinical problems and solutions - maternalclinical problems and solutions - neonataltraining and developmentspecific challenges in specific countries (Afghanistan, Zimbabwe, Egypt and Sri Lanka).
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