Johnsongrass [Sorghum halepense (L.) Pers., ♯3 SORHA] dry weight and johnsongrass culms/ha at harvest were more negatively correlated with soybean yield reductions than the number of johnsongrass plants/ha present at 4 to 6 weeks after planting. However, plant numbers can be determined in sufficient time to implement control measures to prevent yield reduction. Prediction equations for estimating soybean yield at various johnsongrass populations are Ŷ = 1776 + 424e-.023x2 for 0.25-m row spacing and Ŷ = 1668 + 643e-.004x2 for the 1-m row spacing, where Ŷ = estimated yield and x = the number of johnsongrass plants/10 m2. Full-season heavy johnsongrass competition reduced soybean yields from 59 to 88%. Soybeans in the 1-m row spacing were more competitive with low johnsongrass densities than in the 0.25-m row spacing. The johnsongrass-free requirement for soybeans was 4 weeks after planting and soybeans could not tolerate heavy infestations of johnsongrass for more than 5 weeks without loss in yield potential. Application of sethoxydim {2-[1-(ethoxyimino)-butyl]-5-[2-ethylthio)propyl]-3-hydroxy-2-cyclohexen-1-one} at 3 or 4 weeks after planting was effective in controlling heavy infestations of johnsongrass and preventing yield reductions due to competition.