A multiyear study was carried out at two citrus groves with mature trees in southwest Florida in the United States to evaluate the effects of cover cropping on the citrus interrow as a sustainable weed management strategy in the Florida citrus production system. Two cover crop (CC) mixes (legume + non-legume species and only non-legume species) were compared with a no-CC grower standard management (GSM) that utilized the herbicide paraquat for weed suppression in the citrus tree interrow spaces. We gathered data on the biomass and density of both CCs and weeds, during the spring and summer/fall CC planting seasons throughout the study years. Both mixes of CCs effectively reduced weed density in the citrus interrow by 58% to 99% (P < 0.05), depending on the growing season and study locations, compared with GSM. Additionally, there were no significant differences observed between the different CC mixes. Similarly, both CC mixes reduced the weed biomass by 95% to 99% (P < 0.05) in the citrus interrow compared with the GSM. However, weed suppression by CCs varied between growing seasons, mainly due to differences in germination and establishment of the CCs in each season.