Results are presented from campaigns carried out in March and May 2012 across the main channel of the Vlie Inlet in the western Dutch Wadden Sea. On both occasions current velocities and concentrations of suspended particulate matter (SPM) were measured at six stations over one tidal cycle. Concentrations are found to be high only during late ebb and early flood, implying a brief but intense export and import of SPM, respectively. Transport of water and SPM occurs predominantly over the southwestern part of the channel. The tidal prism in the channel varies in the range of 5–7 × 108 m3. Gross amounts of SPM transported during ebb and flood are 6–8 × 106 kg during the first campaign, but only half that amount during the second, possibly due to a different wind direction. The limitations encountered when calculating net effects over a tidal cycle are discussed, such as the fundamental indeterminacy in the duration of the tidal period itself.