With the increasing nationalization of politics, federal politicians have interacted more and more with subnational actors. In particular, the president and governing party have provided selective policy and spending benefits to same-party jurisdictions in order to increase their influence in subnational politics. As a significant amount of federal grants is allocated directly to city governments, we analyze the effects of the federal-city relationship in the federal grant process. Specifically, we examine the effects of the president–mayor party alignment on the allocation of federal block and project grants to 568 medium and large cities from 2005 to 2020 using a two-way (city and year) fixed-effects model. We find that the president favors co-partisan mayors in the distribution of federal grants, specifically co-partisan mayors from (a) secure party cities, (b) cities in states where the governor is also a co-partisan, and (c) secure party cities in states where the governor is also a co-partisan. Digging deeper, we find this form of presidential particularism is almost exclusively a Democratic pursuit.