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This chapter investigates possible future directions of the DOHaD framework. Specifically, it discusses options to translate the framework into the Anthropocene. In a first step, I outline how recent research on epigenetics, the human microbiome, and planetary boundaries challenges notions of origin and development embedded in DOHaD research. I then outline three distinct modes of interdisciplinary collaboration: subordination–service, integration–synthesis, and agonistic–antagonistic. I discuss how each of these modes offers the possibility to conduct research across the nature–culture divide and address human bodies and environments as anthropogenic due to their complex natural, social, and political histories. I conclude that the DOHaD framework needs to embrace the idea of anthropogenic biology to address the challenges of the Anthropocene and take responsibility for the knowledge that it produces in an attempt to shape a politics of habitability for our planet.
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