A regional programme, involving seven national programmes and three international agencies, has been launched in East Africa to promote research on the biological control of cassava green mite, Mononychellus tanajoa (Bondar) sensu lato. The organization and objectives of the programme are described and outline results of the first 2 years of work are reported. Trials to assess losses due to mites were carried out at 10 sites, using acaricides to protect split plots of two to five varieties in each trial; at 6 sites, significant losses of tuber yield were recorded on one or more varieties. Surveys of indigenous natural enemies indicated that the predator complex is similar throughout the region and does not provide adequate green mite control. Two Neotropical phytoseiid predators have so far been introduced for local evaluation. One of these, Neoseiulus idaeus, has been released at 12 sites in three countries; recoveries were made at several sites, but no impact on the pest population was detectable. Plans for further collaborative work are discussed.