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1 results

  • 22 - Neuroimaging of anxiety disorders: commentary

  • from Section III - Anxiety Disorders
    • By Scott L. Rauch, Department of Psychiatry McLean Hospital Harvard Medical School Belmont, MA, USA
  • Edited by Martha E. Shenton, Bruce I. Turetsky, University of Pennsylvania
  • Book:
    Understanding Neuropsychiatric Disorders
    Published online:
    10 January 2011
    Print publication:
    09 December 2010, pp 308-312

  • Summary

    This chapter highlights the diagnosis, pathophysiology, etiology, and clinical utility, as well as trends in the evolution of psychiatric neuroimaging of anxiety disorders such as post-traumatic stress disorder and obsessive-compulsive disorder. Over the past 20 years, the authors have seen a movement toward studies of much larger cohorts of subjects, which helps to mitigate risks of statistical error, by providing greater statistical power and potentially more representative samples. There is a movement toward multi-modal imaging, where data gathered across various methods can bring together structural, functional, and chemical indices to provide greater depth, texture, and convergent validity to findings. Likewise, assessment of inter-regional correlations, and methods that enable finer temporal resolution, reflect greater sophistication in assessing the brain basis of healthy functions as well as diseases and their treatments.