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pericellular microenvironment

The Journal of Anatomy (1)

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Review. Articular cartilage chondrons: form, function and failure
C. ANTHONY POOLE
Journal:

The Journal of Anatomy / Volume 191 / Issue 1 / July 1997

Published online by Cambridge University Press:

01 July 1997, pp. 1-13

Print publication:

July 1997
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The chondrocyte and its pericellular microenvironment together represent the chondron, historically considered the primary structural, functional and metabolic unit of articular and other hyaline cartilages. This review summarises research over the last 10 years to establish the molecular anatomy, functional properties and metabolic contribution of the chondron in articular cartilage homeostasis, and its failure during the initiation and progression of degenerative osteoarthritis.