Host-plant resistance plays an important role in the insect-pest management either alone or in combination with other control methods. A number of sorghum genotypes showing varying levels of resistance to spotted stem borer, Chilo partellus Swinhoe have been identified using natural and artificial infestations. Major resistance mechanisms are antibiosis and tolerance, though some genotypes exhibit ovipositional non-preferences. There have been a number of factors involved in spotted stem borer resistance; a resistant genotype possesses either one or a combination of these traits. Progress has been made in developing borer resistant breeding lines with moderate yield and acceptable grain quality. Borer resistance is a quantitatively inherited trait governed by additive and non-additive genes. Epistatic gene effects are more pronounced under artificial borer infestation. Cytoplasmic effects appear to be present.