This study explored how second language (L2) speakers’ use of multiword sequences in speech predicted perceived fluency ratings while controlling for their utterance fluency. A total of 102 Japanese speakers of English delivered an argumentative speech, which was analyzed for bigram and trigram measures (frequency, proportion, and mutual information) and utterance fluency measures capturing three subdimensions: speed, breakdown, and repair fluency (Tavakoli & Skehan, 2005). Perceived fluency was assessed by 10 experienced L2 raters. Mixed-effects regression analyses revealed that after establishing the parsimonious model solely by UF predictors (marginal R2 = .61), a frequency-based n-gram predictor––bigram proportion––slightly but significantly explained the remaining variance of fluency rating scores (0.8%). The results indicated that multiword sequences in speech had a small but systematic impact on perceived fluency, even controlling for the effects of utterance fluency. This finding contributes to the discussion concerning the role of multiword sequences in fluent speech production.