Field studies were conducted in 2014 and 2015 in Tennessee to examine pyroxasulfone dissipation under field conditions of winter wheat production. Three formulations were examined: (1) a single component active ingredient in an 85% dry flowable, (2) dry flowable formulation in combination of pyroxasulfone+flumioxazin, and (3) a liquid SC formulation of pyroxasulfone+carfentrazone. The liquid formulation is a suspo-emulsion. When averaged across the three studies, the DT 50 were 34.4, 30.2 and 29.9 d for pyroxasulfone plus carfentrazone, pyroxasulfone, and pyroxasulfone plus flumioxazin, respectively. These trends would indicate that formulation had little or no effect on pyroxasulfone dissipation in this experiment. Pyroxasulfone DT 50 in all studies ranged from a low of 15.4 d to a high of 53.3 d, and loss was more rapid under warm, moist conditions. These results indicate that pyroxasulfone would last long enough to provide residual weed control, but would not persist excessively to injure rotational crops.