Darius I overcame rebellions and seized the throne of Babylon, but cuneiform scholarship continued and developed; religious practices did not change, nor did the great buildings on the citadel. The zodiac scheme came into use. The Achaemenid king took Babylonian royal titles and promoted the worship of Marduk for local purposes. Xerxes broke the continuity. Following an uprising, a purge led to the ending of many archives. The province of Babylon was divided in two. Subsequent Achaemenid kings continued to treat Babylon with reverence. Alexander the Great defeated Darius III, entered Babylon, retained the Persian satrap, and moved treasure from Susa and Ecbatana to Babylon. He was recognized as a god. Lack of sons at his premature death precipitated a civil war from which Alexander’s commander Seleucus emerged to take the throne jointly with his son Antiochus. The derelict ziggurat was demolished, but temples and rituals, chronicles and astronomical diaries, continued as before. Aramaic was widely used, and fewer texts were inscribed in cuneiform. Interest in the fall of Assyria and of the Babylonian empire is apparent in Greek literature. Famous scholars include Berossus and named astronomers. Parthians invaded and eventually ended the dynasty.

Hard times for Babylon followed the end of the First Dynasty; but records of two Sealand kings, and the account of magnificent rebuilding of Marduk’s temple by a Kassite king imply wealth and energy. Glass production brought a new source of wealth, and horses were bred for chariots. Marduk was still the supreme god. The top status of the Kassite kings in Babylon was recognized by the pharaohs in Egypt. There cuneiform was used for international correspondence and Babylonian literature used to train local scribes. Foreign wives were taken from Elamite, Assyrian, and Hittite royalty. A top scribe from Babylon served in Assyria, and literature flourished. Boulders recording donations of land were carved with texts and celestial motifs. The office of eunuch is discussed. The Assyrian king raided Babylon, looting literary tablets among other valuables. He took over rule of Bahrain to access Gulf trade. The Kassite kings soon resumed the dynasty but the Elamite king raided and in turn took huge amounts of booty. In the next dynasty, the great Nebuchadnezzar I defeated Elam and wrote a heroic account. As a result of tribal incursions by Arameans, the Aramaic language began to spread, and camels trained for transport opened up desert trade. A library already existed in Babylon.