A body of jurisprudence is emerging in Africa's most active regional courts on the independence of national judiciaries. This article reveals that while regional case law relevantly echoes efforts by municipal courts to safeguard themselves, circumstances demonstrate that such case law requires greater contextualization across systems. In this regard, the traditional paradigm of linking independence to executive appointments does not empirically stand the test of the multiplicity of independence factors, executive-free regimes have not proved effective in safeguarding independence, and legal traditions or judicial systems have increasingly become irrelevant to the effectiveness of any independence regime. Factors that transcend the traditional determinants of executive control include the nature and functions of the court involved, and the history and background of the judicial structure of the country or region. Notably, the discussion also reveals the need to strike a critical balance between individual rights to a fair trial and inter-state directive policy towards judicial independence as set out in the African Charter.