Common cocklebur root and shoot interferences were investigated as factors causing soybean yield reductions in the field. Significant decreases in soybean yield resulted from common cocklebur shoot interference when the two were grown together with the common cocklebur roots confined in plastic bags. Soybean yield decreased further when common cocklebur roots were not confined, but this decrease resulted, in part, from increased common cocklebur shoot growth. Wire mesh cylinders of varying diameters, placed in gaps in the soybean rows and designed to spatially restrict soybean shoot growth, reduced yield more than did gaps alone. When similar cylinders lined with black plastic were placed next to the soybean rows to restrict both within-canopy light and space for soybean shoot growth, soybean yield was reduced most (44%) with concomitant changes in stem height, stem diameter, lodging, and branches, nodes, and pods/plant. Interference of common cocklebur with soybeans resulted primarily from shoot interference, and competition for light within the soybean canopy implicated as the major factor causing the soybean yield reduction.