In this paper, we designed an experiment to research the properties for the stimulated Brillouin scattering (SBS) medium of perfluorocarbon-compounds (PFCs) and perfluoropolyether (PFPE), then we proposed that the selection principle of the high load capacity SBS medium can be used in the high peak power SBS system. The results showed that, for PFCs, perfluorinated hydrocarbons (FC-72) has the highest optical breakdown threshold (OBT); for PFPE, the medium with average molecular weight (AMW) less than 1000 has small medium absorption coefficient (AC) and high OBT, for AMW, greater than 1000, the medium AC becomes high and the OBT becomes low. Further research shows that, for PFPE series SBS medium, the AC increases and the OBT decreases gradually with increasing of AMW. We find some SBS mediums can work stably under high peak power pump, which lays a good foundation for the application of SBS technology in a high-power laser system.